SCREENING OF THYMUS VULGARIS ESSENTIAL OIL AGAINST FUNGI CAUSING DERMATOPHYTOSIS IN HUMAN BEINGS


Neetu Jain, Meenakshi Sharma

Abstract


Objective: The study was designed to determined antidermatophytic activity of Thymus vulgaris essential oil against fungi causing superficial skin infections in human and animal.

Methods: Minimum inhibitory concentration (MIC) of essential oil was screened against selected pathogenic fungi namely Trichophyton rubrum (MTCC 296), T. mentagrophytes (MTCC 7687), Microsporum gypseum (MTCC 4524), M. fulvum(MTCC2837), T. soudanense and T. interdigitale through semi solid agar antifungal susceptibility testing method(SAAS). Minimum fungicidal concentration (MFC) was also determined by modified semi solid agar antifungal susceptibility method. T. soudanense and T. interdigitalis were isolated through TO. KA. VA hair bating technique from animal habitats soil of Jaipur district.

Results: T. vulgaris essential oil exhibited excellent antideramtophytic activity against all selected dermatophytes. Minimum inhibitory concentration was ranged from 0.020±0.000μl/ml to 0.1±0.033 μl/ml. MFC were found little higher than MIC (0.02±0.000μl/ml to.2±0.000μl/ml). M. gypseum was found to be most susceptible fungus as compared to other test fungi.

Conclusion: T. vulgaris was found to be most effective fungicidal agent against human pathogenic fungi. Present findings provide for a rationale basis of a possible utilization of this oil in fields requiring safe and cheap compounds with antiseptic and preservative properties, such as cosmetic, pharmaceutical and food industries.


Keywords


Thymus vulgaris, Essential oil, Dermatophytes, Trichophyton, Microsporum

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About this article

Title

SCREENING OF THYMUS VULGARIS ESSENTIAL OIL AGAINST FUNGI CAUSING DERMATOPHYTOSIS IN HUMAN BEINGS

Keywords

Thymus vulgaris, Essential oil, Dermatophytes, Trichophyton, Microsporum

DOI

10.22159/ijpps.2017v9i10.20054

Date

02-10-2017

Additional Links

Manuscript Submission

Journal

International Journal of Pharmacy and Pharmaceutical Sciences
Vol. 9, Issue 10, 2017 Page: 236-239

Online ISSN

0975-1491

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Authors & Affiliations

Neetu Jain
Laboratory of Microbiology, Department of Botany, University of Rajasthan, Jaipur

Meenakshi Sharma
Laboratory of Microbiology, Department of Botany, University of Rajasthan, Jaipur


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