SYNTHESIS, CHARACTERIZATION AND ANTIBACTERIAL ACTIVITY OF ALUMINIUM OXIDE NANOPARTICLES


Manyasree D., Kiranmayi P., Ravi Kumar R. V. S. S. N.

Abstract


Objective: In the present study, synthesized alumina (Al2O3) nanoparticles were characterized and their antibacterial activity against gram positive and gram negative organisms were studied.

Methods: The synthesis was carried out by coprecipitation method using aluminium sulfate and NaOH as precursors. The synthesized aluminium oxide nanoparticles were characterized by using X-ray diffraction (XRD), Fourier transforms infrared spectroscopy (FT-IR) and scanning electron microscope (SEM) with Energy Dispersive X-ray Analysis (EDX) techniques. Besides, this study determines the antibacterial activity and minimum inhibitory concentration (MIC) of Al2O3 nanoparticles against gram-positive (Staphylococcus aureus and Streptococcus mutans) and gram-negative (E. coli and Proteus vulgaris) bacteria.

Results: The average crystallite size of Al2O3 nanoparticles was found to be 35 nm by X-ray diffraction. FT-IR spectrum exhibited the peaks at 615 and 636 were assigned to the aluminium oxide stretching. The EDX measurements indicated the presence of Al along with O peaks. It indicates the purity of the sample. The antimicrobial assay revealed that E. coli showed a maximum zone of inhibition (39 mm) at 50 mg/ml concentration of Al2O3 nanoparticles.

Conclusion: In conclusion, aluminium oxide is a good antibacterial agent against both gram positive and gram-negative organisms.


Keywords


Al2O3 nanoparticles, XRD, FTIR, SEM, EDX, Antibacterial activity and MIC

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About this article

Title

SYNTHESIS, CHARACTERIZATION AND ANTIBACTERIAL ACTIVITY OF ALUMINIUM OXIDE NANOPARTICLES

Keywords

Al2O3 nanoparticles, XRD, FTIR, SEM, EDX, Antibacterial activity and MIC

DOI

10.22159/ijpps.2018v10i1.20636

Date

01-01-2018

Additional Links

Manuscript Submission

Journal

International Journal of Pharmacy and Pharmaceutical Sciences
Vol 10, Issue 1, 2018 Page: 32-35

Online ISSN

0975-1491

Authors & Affiliations

Manyasree D.
Department of Biochemistry, Acharya Nagarjuna University, Nagarjuna Nagar 522510, India
India

Kiranmayi P.
Department of Biochemistry, Acharya Nagarjuna University, Nagarjuna Nagar 522510, India
India

Ravi Kumar R. V. S. S. N.
Department of Physics, Acharya Nagarjuna University, Nagarjuna Nagar 522510, India
India


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