ASSESSMENT OF DRUG RELATED PROBLEMS IN PATIENTS WITH CHRONIC DISEASES IN THE GENERAL MEDICINE UNITS OF A TERTIARY CARE HOSPITAL


Mannu Meria Wincent, D. Potrilingam, Anagha V., Sajith Chacko Jacob, Andhuvan G.

Abstract


Objective: Patients with chronic diseases are more prone to develop drug-related problems (DRPs), which can further worsen their quality of life. The aim of this study was to determine factors and medications associated with DRPs in patients with chronic disease.

Methods: This prospective interventional study was conducted for a duration of 6 mo in the in-patients of general medicine department of PSG Hospital, Coimbatore. DRPs were identified, assessed and recorded as per pharmaceutical care network Europe (PCNE) V5.01 criteria. Chi-square and correlation test were used to analyze the data for identifying factors associated with DRPs.

Results: A total of 137 patients were enrolled for the study, of which 66 patients developed DRPs. The most prevalent DRP was found to be drug choice problem. The major causes of DRPs were found to be drug and dose selection. Antidiabetic drugs were found to be more associated with drug-related problems. The incidence of drug-related problems was high in patients aged between 50 to 59 y. Association between gender, length of hospital stays and polypharmacy with DRPs was found to be statistically significant. 58.33% of the total drug-related problems were completely solved and 19.05% were partially solved.

Conclusion: The incidence of DRPs in the General Medicine department of the hospital was high. The use of an appropriate tool such as PCNE may assist pharmacists and other healthcare professionals to systematically identify, categorize and report drug-related problems.


Keywords


Drug-related problems, Chronic diseases, PCNE, Association

| PDF | HTML |

References


Adusumilli PK, Adepu R. Drug-related problems: an overview of various classification systems. Asian J Pharm Clin Res 2014;7:7-10.

Pankaj Agarwal, Ajay Sachan, Rajeev K Singla, Pankaj Jain. Statistical analysis of medication errors in Delhi, India. Indo Global J Pharm Sci 2012;2:88-97.

Shalini Sivadasan, Mohan Sellapan. A study on the awareness and attitude towards pharmacovigilance and adverse drug reaction reporting among nursing students in a private university, Malaysia. Int J Curr Pharm Res 2015;7:84-9.

Hasniza Zaman Huri, Lee Chari Ling. Drug-related problems in type 2 diabetes mellitus patients with dyslipidemia. Bio Med Central 2013;13:1192.

Pharmaceutical Care Network Europe Foundation. PCNE classification for drug-related problems version 5.01; 2006.

http://www.pcne.org/sig/drp/documents/PCNE%20classification%20V5.01.pdf

India: Towards Universal Health Coverage 3, chronic diseases and injuries in India. Available from: http://www.who.int/ macrohealth/action/NCMH_Burden%2520of%2520disease_(29%2520Sep%25202005).pdf. [Last accessed on 20 Jun 2017]

Harikesh Maurya, Tirath Kumar. A review on comprehensive overview in the management of nephritic disorders. J Crit Rev 2016;3:34-43.

Sarfaraz Mohammed, Sanjay Poudel, Fernance Laloo, Arjun Madhur, Rinson Robert, Binu Mathew. Assessment of drug related problems in a tertiary care teaching hospital, India. Asian J Pharm Clin Res 2017;10:310-3.

Ganachari MS, Mahendra Kumar BJ, Shashikala C Wali, Fibin M. Assessment of drug therapy interventions by a clinical pharmacist in a tertiary care hospital. Indian J Pharm Practice 2010;3:22-8.

Bhupathy Alagiriswami, Madhan Ramesh, Gurumurthy Parthasarathi, Hatthur Basavanagowdappa. A study of clinical pharmacist-initiated changes in drug therapy in a teaching hospital. Indian J Pharm Practice 2009;1:36-45.

Maheshkumar VP, Dhanapal CK, Ramakrishna Rao M. Outcomes of clinical pharmacist’s interventions in solving drug-related problems in geriatric patients of a rural teaching hospital. Pharma Innovation J 2016;5:99-105.

Javedh Shareef, Sandeep B, CS Shastry. Assessment of drug-related problems in a patient with cardiovascular diseases in a tertiary care teaching hospital. J Pharm Care 2014;2:70-6.

Sujit Rambhade, Anup Chakarborty, Anand Shrivastava, Umesh K. Patil and Ashish Rambhade. A survey on polypharmacy and use of inappropriate medications. Toxicol Int 2012;19:68-73.




About this article

Title

ASSESSMENT OF DRUG RELATED PROBLEMS IN PATIENTS WITH CHRONIC DISEASES IN THE GENERAL MEDICINE UNITS OF A TERTIARY CARE HOSPITAL

Keywords

Drug-related problems, Chronic diseases, PCNE, Association

DOI

10.22159/ijpps.2017v9i12.21660

Date

01-12-2017

Additional Links

Manuscript Submission

Journal

International Journal of Pharmacy and Pharmaceutical Sciences
Vol 9, Issue 12, 2017 Page: 194-200

Online ISSN

0975-1491

Statistics

42 Views | 4 Downloads

Authors & Affiliations

Mannu Meria Wincent
Department of Pharmacy Practice, PSG College of Pharmacy, Coimbatore, Tamilnadu, India
India

D. Potrilingam
Department of Pharmacy Practice, PSG College of Pharmacy, Coimbatore, Tamilnadu, India

Anagha V.
Department of Pharmacy Practice, PSG College of Pharmacy, Coimbatore, Tamilnadu, India

Sajith Chacko Jacob
Department of Pharmacy Practice, PSG College of Pharmacy, Coimbatore, Tamilnadu, India

Andhuvan G.
Department of Pharmacy Practice, PSG College of Pharmacy, Coimbatore, Tamilnadu, India


Article Tools



Refbacks

  • There are currently no refbacks.