A COMPREHENSIVE REVIEW ON ULCER HEALING POTENTIAL OF MEDICINAL PLANTS


Divya Sharma, Shailendra Bhatt

Abstract


Peptic ulcers are a broad term that includes ulcers of gastrointestinal tract. The formation of peptic ulcers is due to the presence of acid, peptic activity in gastric juice and a breakdown in mucosal defenses. There are two main factors that can disrupt the mucosal resistance to injuryare, non-steroidal anti-inflammatory drugs and H. pylori infection. A number of anti-ulcer drugs such as proton pump inhibitors and H2 receptor antagonists are used for the treatment of peptic ulcer, but these drugs has shown incidence of relapses, side effects, and drug interactions. Plant origin drugs are gaining popularity to treat number of disorders, including peptic ulcer. There is a need for less toxic and potentanti-ulcerogenic drugs. Since long time plant extracts are used to produce promising anti-ulcerogenic effects. The present work was carried out to investigate the possible preventive anti-ulcerogenic effect. In the present study we have reviewed most commonly employed herbal medicines and various animal models which were used in the screening of anti ulcer activity.

Keywords:  Anti-ulcer, Medicinal plant, Animal model.

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About this article

Title

A COMPREHENSIVE REVIEW ON ULCER HEALING POTENTIAL OF MEDICINAL PLANTS

Date

01-11-2014

Additional Links

Manuscript Submission

Journal

International Journal of Pharmacy and Pharmaceutical Sciences
Vol 6, Issue 10, 2014 Page: 3-11

Online ISSN

0975-1491

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360 Views | 183 Downloads

Authors & Affiliations

Divya Sharma
MAHARISHI ARVIND INSTITUTE OF PHARMACY, MANSAROVAR, JAIPUR
India

Shailendra Bhatt
MAHARISHI ARVIND INSTITUTE OF PHARMACY, MANSAROVAR, JAIPUR
India


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