• Basavaraj C Metri Department of Microbiology BLDEU’s Shri B M Patil Medical college Bijapur Karnataka 586103
  • P Jyothi Department of Microbiology BLDEU’s Shri B M Patil Medical college Bijapur Karnataka 586103


Objectives: Urinary tract infections (UTIs) are one of the most common bacterial infections affecting humans throughout their life span. There is paucity of literature in relation to pathogenesis of UTIs caused by Pseudomonas aeruginosa. Therefore the current study was conducted to know the antibiotic sensitivity pattern of P. aeruginosa isolated from UTIs from our hospital.

Methods: The study was carried out over a period of 3 years from January 2010 to December 2012. Urine specimens from both outpatients and inpatients of our hospital were processed. Urine samples which yielded the growth of Pseudomonas aeruginosa were included in the study

Results: Among females, frequency of UTI was more among 21-50 years age groups and among males elderly patients were more commonly affected. The most active antimicrobial agent against Pseudomonas aeruginosa isolates were piperacillin-tazobactum (54% sensitive), closely followed by Cefoparazone –salbactam (48%).

Conclusion: This study stresses the importance of prior knowledge of the sensitivity pattern of the pathogen. Treatment should be given only after culture and sensitivity has been performed which will prevent the misuse of antibiotics and reduce the development of drug resistance among bacteria


Keywords: Antimicrobial resistance, Pseudomonas aeruginosa, Urinary tract infections.


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Author Biography

Basavaraj C Metri, Department of Microbiology BLDEU’s Shri B M Patil Medical college Bijapur Karnataka 586103

     Associate professor

     Department of Microbiology

                       BLDEU’s Shri B M Patil Medical college

                       Bijapur –Karnataka-586103                       


1. Mittal R, Aggarwal S, Sharma S, Chhibber S, Harjai K. Urinary tract infections caused by Pseudomonas aeruginosa: a minireview. J Infect Public Health 2009;2:101-11.
2. Gales AC, Jones RN, Turnidge J, Rennie R, Ramphal R. Characterization of Pseudomonas aeruginosa isolates: occurrence rates, antimicrobial susceptibility patterns, and molecular typing in the global SENTRY antimicrobial surveillance program, 1997–1999. Clin Infect Dis 2001;32(Suppl 2):S146–55.
3. Kerr KG, Snelling AM. Pseudomonas aeruginosa: a formidable and ever-present adversary. J Hospital Infect 2009;73:338-44.
4. Mittal R, Khandwaha RK, Gupta V, Mittal PK, Harjai K. Phenotypic characters of urinary isolates of Pseudomonas aeruginosa and their association with mouse renal colonization. Indian J Med Res 2006;123:67-72.
5. Hryniewicz K, Szczypa K, Sulikowska A, Jankowski K, Betlejewska K, Hryniewicz W. Antibiotic susceptibility of bacterial strain isolated from urinary tract infections in Poland. J Antimicrob Chemother 2001;47:773–80.
6. Collee JG, Duguid JP, Fraser AG, Marmion BP, Simmons A. Laboratory strategy in diagnosis of infective syndromes. In: Collee JG, Duguid JP, Fraser AG, Marmion BP, Simmons A (editors). Mackie and McCartney Practical Medical Microbiology, 14th ed. London: Churchill Livingstone; 1996. p. 53-94.
7. Cruickshank R, Duguid JP, Marmion BP. Tests for identification of bacteria. In: Medical Microbiology. 12th ed. London: Churchill Livingstone; 1975. p. 170-89.
8. Clinical and Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing; 16th informational supplement. M100-S16. Clinical and Laboratory Standards Institute, Wayne, PA; 2006.
9. Gupta K. Emerging antibiotic resistance in urinary tract pathogens. Infect Dis Clin North Am 2003;17:243–59.
10. Akoachere J-FTK, Yvonne S, Akum NH, Seraphine EN. Etiologic profile and antimicrobial susceptibility of community acquired urinary tract infection in two Cameroonian towns. BMC Res Notes 2012;5:219.
11. Metri Basavaraj C, P Jyothi. Antimicrobial resistance of Klebsiella pneumoniae strains from patients with urinary tract infections in SBMPMC hospital Bijapur, India. Int J Pharm Bio Sci 2014;5(3):376–82.
12. Das RN, Chandrashekhar TS, Joshi HS, Gurung M, Shrestha N, Shivananda PG. Frequency and susceptibility profile of pathogens causing urinary tract infections at a tertiary care hospital in western Nepal. Singapore Med J 2006;47:281-5.
13. Foxman B. Epidemiology of urinary tract infections: incidence, morbidity, and economic costs. American J Med 2002;113:1S-13S.
14. Souli M, Galani I, Giamarellou H. Emergence of extensively drug-resistant and pandrug-resistant Gram-negative bacilli in Europe. Eurosurveillance 2008;13:1.
15. Aparna V, Mohanalakshmi N, Dineshkumar K, Hopper W. Identification of inhibitors for rnd efflux pump of Pseudomonas aeruginosa using structure-based pharmacophore modeling approach. Int J Pharm Pharm Sci 2014;6:84-9.
16. Pai V, Nair B. Etiology and sensitivity of uropathogens in outpatients and inpatients with urinary tract infection: Implications on empiric therapy. Ann Trop Med Public Health 2012;5:181-4.
17. Khamenah ZR, Afshar AT. Antimicrobial susceptibility pattern of urinary tract pathogens. Saudi J Kidney Dis Transpl 2009;20:251-3.
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How to Cite
Metri, B. C., and P. Jyothi. “ANTIMICROBIAL RESISTANCE OF PSEUDOMONAS AERUGINOSA STRAINS FROM PATIENTS WITH URINARY TRACT INFECTIONS IN SBMPMC HOSPITAL BIJAPUR, INDIA”. International Journal of Pharmacy and Pharmaceutical Sciences, Vol. 6, no. 9, 1, pp. 479-81,
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