DEVELOPMENT OF ANTI-WRINKLE CREAM FROM PUERARIA CANDOLLEI VAR. MIRIFICA (AIRY SHAW AND SUVAT.) NIYOMDHAM, â€œKWAO KRUA KAOâ€ FOR MENOPAUSAL WOMEN
Objective: The aim of this study was to incorporateÂ PerariaÂ candolleiÂ var.Â mirificaÂ extract into the cream, to evaluate the physical properties and to conduct the skin tests in participants.
Methods: PuerariaÂ candolleiÂ var.Â mirificaÂ was extracted with 95% ethanol to obtain crude pueraria extract (PCM). Crude PCM was developed as an anti-wrinkle PCM cream (B) intended for menopausal women. PCM cream was evaluated for stability of pH and viscosity, primary skin irritation, wrinkle reduction and moisturizing as well as customer satisfaction. Cream base (A) and cream purchased from the market (C) were used for comparison. ANOVA post hoc Turkey was used to analyze the variance (pï€¼0.05) of the mean comparisons between groups by cluster analysis.Â
Results: The PCM cream appeared as white color, pH was 6.80, and viscosity was 4.069Â±0.01 Pa. s, as well as physical characteristic and texture, were acceptable and no irritating reaction. PCM cream exhibited a similar level of moisturizer as cream A and C. The PCM cream revealed an ability to decrease the wrinkle surface and wrinkle volume after applied for 7 and 14 d that shows the activity of this product performed from the PCM extract. Satisfaction of PCM cream showed good acceptance.
Conclusion: These results suggest that PCM cream has the ability to reduce skin wrinkles. It is a good product for postmenopausal women and may also be of benefit for the general population for protection skin wrinkle.
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