PHENOLIC CONTENTS, ANTIBACTERIAL AND ANTIOXIDANT ACTIVITIES OF FLOWER, LEAF AND STEM EXTRACTS OF FERULAGO ANGULATA (SCHLECHT) BOISS

  • Farideh Azarbani Lorestan University
  • Zeinab Saki Department of Chemistry, Lorestan University, Khorramabad, Iran
  • Ali Zareei Lorestan University
  • Abdolnasser Mohammadi Lorestan University

Abstract

Objective: Ferulago angulata known as Chavir is an Iranian endemic plant that has been used as the food preservative and natural flavor since long times. In the present study, antibacterial and antioxidant activities of aqueous and methanol extracts from flower, leaf and stem of F. angulata (Schlecht.) Boiss from Lorestan Province of Iran were evaluated. Total phenol, flavonoid and anthocyanin contents were also determined.

Methods: Antibacterial activity was studied by disc diffusion method. Diphenylpicrylhydrazyl (DPPH) assay was used to determine the antioxidant property. The total phenol, flavonoid and anthocyanin contents were measured by Folin Ciocalteu, AlCl3 and pH differential methods, respectively.

Results: None of the sample extracts showed significant antibacterial activity against tested pathogens. All extracts had inhibitory activity on DPPH radicals with concentration-dependent manner. IC50 values ranged from 214±8.2 to 1606±94.4 µg/ml. The total phenol, flavonoid and anthocyanin contents were in the range of 59±0.017 to 483.5±0.098 mg of Gallic acid equivalents per g of dried extract, 0.5±0.004 to 539±0.29 mg of Quercetin equivalents per g of dried extract and 0.43±0.02 to 4.2±0.82 mg Cyanidin-3-glucoside, respectively.

Conclusion: The Flower aqueous extract exhibited the maximum phenolic compounds and antioxidant activity but, the stem methanol extract was the weakest one.

 

Keywords: Ferulago angulata, Antibacterial, Antioxidant, Phenol, Flavonoid, Anthocyanin.

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Author Biographies

Farideh Azarbani, Lorestan University
Department of Biology
Zeinab Saki, Department of Chemistry, Lorestan University, Khorramabad, Iran
Department of Chemistry
Ali Zareei, Lorestan University
Department of Biology
Abdolnasser Mohammadi, Lorestan University
Department of Biology

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How to Cite
Azarbani, F., Z. Saki, A. Zareei, and A. Mohammadi. “PHENOLIC CONTENTS, ANTIBACTERIAL AND ANTIOXIDANT ACTIVITIES OF FLOWER, LEAF AND STEM EXTRACTS OF FERULAGO ANGULATA (SCHLECHT) BOISS”. International Journal of Pharmacy and Pharmaceutical Sciences, Vol. 6, no. 10, 1, pp. 123-5, https://innovareacademics.in/journals/index.php/ijpps/article/view/2537.
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