ANTIOXIDANT AND ANTHELMINTIC POTENTIAL OF THE STEM & LEAVES OF WHITE ABRUS
Introduction: World Health Organization (WHO) appreciates the importance of medicinal plants for public health care in developing nations. White Abrus (Abrus precatorius Linn) have important role in traditional medicine, its seeds, bark, leaves and stem are medicinal.
Objective: The potential of the leaves and stem of this plant as an antioxidant and anthelmintic agents were evaluated.
Methods: All the analysis was done according to standard protocols.
Results: The methanolic extract produced significant anthelmintic and antioxidant properties in a dose-dependent manner. DPPH free radical scavenging assay of leaf and stem exhibited IC 50 values of 275 Â±0.83 Î¼g/ml and 170 Â± 0.90 Î¼g/ml respectively. At 1000 Î¼g/ml concentration both leaf and stem shows maximum radical scavenging activity (93 % & 98 %).
Superoxide anion scavenging assay also resulted promising activity with IC 50 values 85Â± 0.83Î¼g/ml and 80Â± 0.90Î¼g/ml respectively for leaf and stem. The percentage scavenging of super oxide radical surged with the enhanced concentration of plant extracts. The maximum scavenging activity of plant extract was at 1000 Î¼g/ml concentration, 80 % and 92% respectively in leaf and stem extracts.
Preliminary phytochemical screening revealed the presence of saponins, steroids, flavonoids, terpenoids, cardiac glycosides and phenols in both stem and leaves that may be the reason for its biological properties.
Conclusion: The findings of this study indicate that this plant is medicinal with prominent antioxidant and anthelmintic property.
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