A COMPARATIVE STUDY ON THE IN-VITRO ANTIMICROBIAL ACTIVITY OF THE ROOTS OF FOUR THOTTEA SPECIES


Anilkumar Es, Mathew Dan, Nishanth Kumar S, Dileep Kumar B S, Latha P G

Abstract


Objective: The main objective of the present study was to investigate the antimicrobial activity of the methanol extract of the roots of four Thottea species.

Methods: The root extracts of four Thottea species were subjected to antimicrobial assay by Minimum Inhibitory Concentration (MIC) and Agar Disc diffusion Assay against various medically important pathogens.

Results: It is evident from the study that. Significant antibacterial activity was recorded by Thottea sivarajanii and highest activity was recorded against Pseudomonas aeruginosa and Staphylococcus epidermis (64 µg/ml). Out of the four extracts tested for antifungal activity, Thottea barberi and Thottea ponmudiana recorded significant antifungal activity and the highest activity was recorded by T. barberi against Trichophyton rubrum (16 µg/ml).

Conclusion: Results offer a scientific basis for the traditional use of Thottea species in the treatment of microbial infections, showing that the plant extract has an enormous potential as a prospective alternative drug against microbial pathogens. The present study lays the basis for future studies, to validate the possible use of Thottea species as a candidate in the treatment of microbial infections.

 


Keywords


Antimicrobial activity, Thottea species, MIC, Methanol extract.

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About this article

Title

A COMPARATIVE STUDY ON THE IN-VITRO ANTIMICROBIAL ACTIVITY OF THE ROOTS OF FOUR THOTTEA SPECIES

Keywords

Antimicrobial activity, Thottea species, MIC, Methanol extract.

Date

01-11-2014

Additional Links

Manuscript Submission

Journal

International Journal of Pharmacy and Pharmaceutical Sciences
Vol 6, Issue 10, 2014 Page: 444-447

Online ISSN

0975-1491

Statistics

141 Views | 63 Downloads

Authors & Affiliations

Anilkumar Es
JNTBGRI, TRIVANDRUM

Mathew Dan
Jawaharlal Nehru Tropical Botanic Garden and Research Institute
India

Nishanth Kumar S
Interdisciplinary Science and Technology
India

Dileep Kumar B S
Interdisciplinary Science and Technology
India

Latha P G
Jawaharlal Nehru Tropical Botanic Garden and Research Institute
India


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