PARACETAMOL DISPENSING PRACTICE OF GOVERNMENT HEALTH CLINICS POST INFANTS’ VACCINATION IN MALAYSIA

  • NURAIN SULEIMAN Pharmaceutical Services Division, Johor State Health Department, Ministry of Health Malaysia, a/o Jalan Persiaran Permai, 81200 Johor Bahru, Johor, Malaysia
  • SITI HADIJAH SHAMSUDIN Kulliyyah of Pharmacy, International Islamic University Malaysia, Jalan Sultan Ahmad Shah, Bandar Indera Mahkota, 25200 Kuantan, Pahang, Malaysia
  • RAZMAN MOHD RUS Kulliyyah of Medicine, International Islamic University Malaysia, Jalan Sultan Ahmad Shah, Bandar Indera Mahkota, 25200 Kuantan, Pahang, Malaysia
  • SAMSUL DRAMAN Kulliyyah of Medicine, International Islamic University Malaysia, Jalan Sultan Ahmad Shah, Bandar Indera Mahkota, 25200 Kuantan, Pahang, Malaysia

Abstract

Objective: This study obtained information on Paracetamol (PCM) Dispensing Practice of Government Health Clinics (GHC) post infants’ vaccination in Malaysia as well as identify its possible factors.


Methods: This descriptive cross-sectional retrospective study (with convenient sampling) using a data collection form (DCF) to collect data. The pharmacist who is the representative of the GHC filled the DCF. Potential risk factors were evaluated by Pearson chi-square tests (expected count<5 is<20%) for an independent sample.


Results: A total number of 254 samples were collected all over Malaysia within the period of data collection, but only 248 that met inclusion criteria. The PCM dispensing practice of GHC in Malaysia for a total period of 3 y back (from 2015-2017), tend not to give PCM post immunization with respect to age of the upon vaccination and types of vaccination, conversely for gender. Trends of PCM dispensing practice were increasing for “Not Give PCM” with respect to gender, age of the baby upon vaccination, and types of vaccination from 2015 till 2017. The PCM dispensing practice had no association with no statistically significant value (p=0.804) on genders and a weak positive association with statistically significant value (p<0.05 each) on age of the baby (≤ 1year) upon vaccination and types of vaccination.


Conclusion: Future research which may include the actual practice in which practices of prescribers or mother may be conducted in determining more accurate data on the giving PCM post infant’s vaccination.

Keywords: Paracetamol, Dispensing, Infants, Vaccination

Downloads

Download data is not yet available.

References

1. Prymula R, Siegrist CA, Chlibek R, Zemlickova H, Vackova M, Smetana J, et al. Effect of prophylactic paracetamol administration at time of vaccination on febrile reactions and antibody responses in children: two open-label, randomised controlled trials. Lancet 2009;374:1339-50.
2. Beasley R, Clayton T, Crane J, Von Mutius E, Lai CK, Montefort S, et al. Association between paracetamol use in infancy and childhood, and risk of asthma, rhinoconjunctivitis, and eczema in children aged 6–7 y: analysis from phase three of the ISAAC programme. Lancet 2008;372:1039-48.
3. Le Saux N, Barrowman NJ, Moore DL, Whiting S, Scheifele D, Halperin S. Decrease in hospital admissions for febrile seizures and reports of hypotonic-hyporesponsive episodes presenting to hospital emergency departments since switching to acellular pertussis vaccine in Canada: a report from impact. Pediatrics 2003;112:e348-e348.
4. Atkinson W, Iskander JK, Pickering LK, Schwartz B, Watson JC, Weniger BG. General recommendations on immunization; recommendations of the advisory committee on immunizations practices (ACIP) and the American academy of family physicians (AAFP). MMWR Recomm Rep 2002;51:1-35.
5. College of Paediatrics Malaysian Immunization Manual. Kuala Lumpur: Academy of Medicine of Malaysia; 2001.
6. Public Health Department. National Immunization Programme for Nurses Guideline. Kuala Lumpur: Ministry of Health Malaysia; 2008.
7. Jackson LA, Peterson D, Dunn J, Hambidge SJ, Dunstan M, Starkovich P, et al. A Randomized placebo-controlled trial of acetominophen for prevention of post-vaccination fever in infants. PLoS ONE 2011;6:e20102.
8. Coe, Robert. "It's the effect size, stupid: What effect size is and why it is important," Durham: University of Durham; 2002.
9. Steve Simon, “StATS: What is a phi coefficient?,” Children's Mercy Hospital. Available from: http://www.pmean.com/ definitions/phi.htm [Last accessed on 09 Jan 2018].
Statistics
310 Views | 93 Downloads
Citatons
How to Cite
SULEIMAN, N., S. H. SHAMSUDIN, R. M. RUS, and S. DRAMAN. “PARACETAMOL DISPENSING PRACTICE OF GOVERNMENT HEALTH CLINICS POST INFANTS’ VACCINATION IN MALAYSIA”. International Journal of Pharmacy and Pharmaceutical Sciences, Vol. 11, no. 10, Oct. 2019, pp. 33-39, doi:10.22159/ijpps.2019v11i10.33489.
Section
Original Article(s)