• DANG XUAN CUONG Nha Trang Institute of Technology Application and Research, VAST, Khanh Hoa, Vietnam
  • VU NGOC BOI Faculty of Food Technology, Nha Trang University, MOET, Khanh Hoa, Vietnam,
  • TRAN KHAC TRI NHAN Phu Yen Vocational College, Phu Yen, Vietnam
  • DINH HUU DONG Ho Chi Minh University of Food Industry, MOET, Ho Chi Minh, Vietnam
  • THAI MINH QUANG Institute of Oceanography, VAST, Khanh Hoa, Vietnam
  • PHAM THI KIM TRAM Biotechnology Center of Ho Chi Minh City, Department of Agriculture and Rural Development, Ho Chi Minh, Vietnam
  • DANG THI THANH TUYEN Faculty of Food Technology, Nha Trang University, MOET, Khanh Hoa, Vietnam


Objective: To investigate the content and antioxidant activities of polyphenol, the correlation between polyphenol content and their antioxidant activities, and phytochemistry compositions of different extracts from marine sponge Aaptos suberitoides commonly found growing in Nhatrang bay, Vietnam orienting application into functional food and pharmacy.

Methods: Evaluating the toxicity of antioxidant polyphenol powder preparing from the initial concentrated extract was by the adjusted Behrens Karber method and a correlation between polyphenol content and antioxidant activities basing on the Pearson coefficient in Excel. Separating antioxidant polyphenol content was base on solvents polarization of n-hexane, chloroform, ethanol, ethyl acetate and n-butanol which the quantification of polyphenol content and antioxidant activities, and preliminary phytochemical compositions qualitative.

Results: Antioxidant polyphenol powder did not affect mice weight during the assay time of 28 d. Polyphenol content and antioxidant activities got the highest value at chloroform extract in comparison to other extracts, a significant difference (p<0.05) and strong correlation (R2>0.9). Polyphenol content (122.682 mg gallic acid equivalent ml-1), total antioxidant activity (368.183 mg ascorbic acid equivalent ml-1), reducing power activity (24.08 mg FeSO4 equivalent ml-1) and DPPH scavenging (72.48±1.54 %) were the highest values. Alkaloids, flavonoids, steroids, tannins and triterpenoids existed in initial methanol extract. Weakly polarized polyphenol content was 70.27% in comparison to initial methanol extract.

Conclusion: Antioxidant polyphenol of sponge Aaptos suberitoides has the potential for application into the field of functional food and pharmaceuticals.

Keywords: Aaptos suberitoides, Antioxidant, Phytochemistry, Polyphenol, Sponge


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How to Cite
XUAN CUONG, D., V. N. BOI, T. K. T. NHAN, D. H. DONG, T. M. QUANG, P. T. KIM TRAM, and D. T. T. TUYEN. “Dr. PI POLYPHENOL CONTENT, PHYTOCHEMISTRY COMPOSITIONS AND ANTIOXIDANT ACTIVITY OF DIFFERENT EXTRACTS FROM MARINE SPONGE AAPTOS SUBERITOIDES GROWN IN NHATRANG BAY, VIETNAM”. International Journal of Pharmacy and Pharmaceutical Sciences, Vol. 11, no. 9, Aug. 2019, pp. 80-86, doi:10.22159/ijpps.2019v11i9.34003.
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