• NIKHIL KHANDALE Department of Pharmaceutical Analysis, School of Pharmaceutical Sciences, Lovely Professional University, Jalandhar Delhi G. T. Road, Phagwara (Punjab) 144411 https://orcid.org/0000-0001-7654-3595
  • MANGESH S. GHODKE Department of Pharmaceutical Chemistry, Shreeyash Institute of Pharmaceutical Education and Research, Aurangabad (MS) 431010 https://orcid.org/0000-0002-3353-2455




Indole, Antiviral, Anticonvulsant, Anti-inflammatory, Analgesic, Antimicrobial and anticancer


In general, heterocyclic compounds are rich in pharmacologically active chemicals. Among them are anti-inflammatory, antitubercular, anti-HIV, antimalarial, antidiabetic, anticonvulsants, analgesics, antihypertensive, antifungal, anticancer, antidepressant, antioxidant, and antimicrobial compounds. Due to their wide range of activity in the fields of drug design, Heterocycles occupy a salient place in chemistry. One of the most hopeful heterocycles found in natural and synthetic sources is the indole scaffold which possesses variety of biological activity, including anti-inflammatory, antitubercular, anti-HIV, antimalarial, antidiabetic, anticonvulsants, analgesics, antihypertensive, antifungal, anticancer, antidepressant, antioxidant, and antimicrobial, etc. This review aimed to highlight the synthetic perspective on the development of indole-based analogs. This study aimed to offer clear information on the current development of indoles as anticonvulsant, anticancer, and anti-inflammatory agents.


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How to Cite

KHANDALE, N., and M. S. GHODKE. “EXPLORING POTENTIAL OF INDOLE DERIVATIVES: A BRIEF REVIEW”. International Journal of Pharmacy and Pharmaceutical Sciences, vol. 15, no. 3, Mar. 2023, pp. 1-14, doi:10.22159/ijpps.2023v15i3.46727.



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