Khamsah Suryati Mohd, Mohammed Al-kassim Hassan, Wan-atirah Azemin, Saravanan Dharmaraj


Cancer is one of the leading causes of morbidity and mortality globally. The drawbacks of conventional chemotherapy such as resistance, lack of specificity, severe toxicity warrant the need to explore alternative approach for the treatment of cancer. Antimicrobial peptides are part of the innate defense mechanism of all organisms and have been developed as potential alternatives in combatting infectious diseases. In addition, anticancer effects of many peptides have been reported with remarkable prospects in some in vitro studies especially on breast, cervical and lung cancer cell lines, and in vivo murine tumour xenografts. This review summarizes the reports on the activities of some selected anticancer peptides on various cancer cell lines.


Antimicrobial peptides, Anticancer/antitumour peptides, Host defense peptides

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Antimicrobial peptides, Anticancer/antitumour peptides, Host defense peptides



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International Journal of Pharmacy and Pharmaceutical Sciences
Vol 7, Issue 4, 2015 Page: 19-26

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Authors & Affiliations

Khamsah Suryati Mohd
Faculty of Bioresources and Food Industry, Universiti Sultan Zainal Abidin, Campus Tembila, 22200 Besut, Terengganu, Malaysia

Mohammed Al-kassim Hassan
Universiti Sultan Zainal Abidin

Wan-atirah Azemin
Universiti Sultan Zainal Abidin

Saravanan Dharmaraj
Universiti Sultan Zainal Abidin

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