ANTI-ANEMIC ACTIVITY OF SPROUTS OF VIGNA RADIATA L. IN MALE ALBINO RATS

  • Manikandaselvi S. PG and Research Department of Biochemistry, S. T. E. T Women’s College, Mannargudi, Tamilnadu, India
  • David Raj C. SASTRA University
  • Aravind S. SASTRA University
  • Ravikumar R. Vivekanandha College of Arts and Sciences for Women
  • Thinagarbabu R. SASTRA University
  • Nandhini S. SASTRA University

Abstract

Objective: To evaluate the anti-anemic activity of sprouts of Vigna radiata L. against phenyl hydrazine induced anemic rats.

Methods: Rats were divided into 4 groups of 6 each. Group 1 was given normal saline and served as control and all other groups were given 40 mg/kg b. w of phenyl hydrazine for 2 d to induce anemia. Group 3 was treated with Bioferon (230 mg/kg) and served as the standard. Group 4 was treated with sprouted Vigna radiata L. (600 mg/kg bw). All the treatments were given orally. On completion of the experimental period, all the test substance/vehicle-treated rats were sacrificed and the plasma separated was used for estimating various biochemical as well as hematological parameters as per standard procedures.

Results: The experimental rats treated with sprouted Vigna radiata L. at the dose level 600 mg/kg bw for 13 d revealed significant changes in biochemical and hematological parameters compared to phenyl hydrazine induced anemic rats.

Conclusion: The present study concluded that the sprouted Vigna radiata L. inhibits anemia induced by phenyl hydrazine in male albino rats.

 

Keywords: Anemia, Phenyl hydrazine, Vigna radiata L., Bioferon

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How to Cite
S., M., D. R. C., A. S., R. R., T. R., and N. S. “ANTI-ANEMIC ACTIVITY OF SPROUTS OF VIGNA RADIATA L. IN MALE ALBINO RATS”. International Journal of Pharmacy and Pharmaceutical Sciences, Vol. 7, no. 11, Oct. 2015, pp. 263-7, https://innovareacademics.in/journals/index.php/ijpps/article/view/6992.
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