MICROENCAPSULATION OF ELLAGIC ACID FROM POMEGRANATE HUSK AND KARAYA GUM BY SPRAY DRYING

  • Gabriel A. LujÁn-medina Food Research Department, School of Chemistry, Universidad Autonoma de Coahuila, Saltillo 25280, Coahuila, Mexico
  • Janeth Ventura Food Research Department, School of Chemistry, Universidad Autonoma de Coahuila, Saltillo 25280, Coahuila, Mexico
  • Juan A. Ascacio-valdÉs Animal Nutrition Department, Animal Sciences Division. Agrarian Autonomous University “Antonio Narro”. Saltillo 25315, Coahuila, Mexico
  • Miguel A. Cerqueira CEB-Centre of Biological Engineering, University of Minho, Campus de Gualtar, 4710057 Braga Portugal
  • Daniel Boone Villa Food Research Department, School of Chemistry, Universidad Autonoma de Coahuila, Saltillo 25280, Coahuila, Mexico
  • Juan C. Contreras-esquivel Food Research Department, School of Chemistry, Universidad Autonoma de Coahuila, Saltillo 25280, Coahuila, Mexico
  • Miguel A. Aguilar GonzÁlez Laboratory of Characterization of Micro and Nanostructured Materials, Metallurgy and Ceramics. Centre for Research and Advanced Studies (CINVESTAV). National Polytechnic Institute. Ramos Arizpe 25903, Coahuila, Mexico
  • AntÓniovicente . CEB-Centre of Biological Engineering, University of Minho, Campus de Gualtar, 4710057 Braga Portugal
  • CristÓbal N. Aguilar Food Research Department, School of Chemistry, Universidad Autonoma de Coahuila, Saltillo 25280, Coahuila, Mexico

Abstract

Objective: The aim of this study was to obtain and characterize microcapsules with Ellagic Acid (EA) from pomegranate as core material and Karaya Gum (KG) as wall material.

Methods: EA was obtained from dry pomegranate peel powder via methanolysis and quantified by HPLC. Microcapsules were obtained preparing a dispersion containing KG and EA in phosphate buffer pH 8. The dispersion was processed in a spray dryer under specific conditions (inlet temperature at 150 °C, feed flow at 30% and aspirator at 100 %) for obtaining of microcapsules. Fourier transform infrared (FTIR) spectroscopy, differential scanning calorimetry (DSC) and scanning electron microscopy (SEM) were used for characterization.

Results: Obtained material contains 98.03±2.82 mg EA/g of pomegranate peel. FTIR showed that there were changes in the molecular structure of microcapsules referred to raw materials. SEM confirmed that particles obtained had micron-size (1-5 µm). DSC analysis showed that raw materials had glass transition temperatures of 79.58 and 83.41 °C and for microcapsules the value was67.25 °C.

Conclusion: Methanolysis is a viable technique for the obtaining of EA from the peel of pomegranate. KG shows good potential for be used as wall material for EA microencapsulation.

 

Keywords: Pomegranate husk, Ellagic acid, Karaya gum, Spray drier, Microcapsules.

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Author Biographies

Gabriel A. LujÁn-medina, Food Research Department, School of Chemistry, Universidad Autonoma de Coahuila, Saltillo 25280, Coahuila, Mexico
Food Research Department
Janeth Ventura, Food Research Department, School of Chemistry, Universidad Autonoma de Coahuila, Saltillo 25280, Coahuila, Mexico
Food Research Department, Researcher
Juan A. Ascacio-valdÉs, Animal Nutrition Department, Animal Sciences Division. Agrarian Autonomous University “Antonio Narro”. Saltillo 25315, Coahuila, Mexico
Animal Nutrition Department, Pos-doctoral Researcher
Miguel A. Cerqueira, CEB-Centre of Biological Engineering, University of Minho, Campus de Gualtar, 4710057 Braga Portugal
Centre of Biological Engineering, Pos-doctoral Researcher
Daniel Boone Villa, Food Research Department, School of Chemistry, Universidad Autonoma de Coahuila, Saltillo 25280, Coahuila, Mexico
School of Health Sciences. Departament of Food Research, Invited Proffessor
Juan C. Contreras-esquivel, Food Research Department, School of Chemistry, Universidad Autonoma de Coahuila, Saltillo 25280, Coahuila, Mexico
Food Research Department, Researcher
Miguel A. Aguilar GonzÁlez, Laboratory of Characterization of Micro and Nanostructured Materials, Metallurgy and Ceramics. Centre for Research and Advanced Studies (CINVESTAV). National Polytechnic Institute. Ramos Arizpe 25903, Coahuila, Mexico
Laboratory of Characterization of micro and nanostructurated materials, metallurgy and ceramics, Head Researcher
AntÓniovicente ., CEB-Centre of Biological Engineering, University of Minho, Campus de Gualtar, 4710057 Braga Portugal
Centre of Biological Engineering, Associated Proffessor
CristÓbal N. Aguilar, Food Research Department, School of Chemistry, Universidad Autonoma de Coahuila, Saltillo 25280, Coahuila, Mexico
Food Research Department, Researcher

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How to Cite
LujÁn-medinaG. A., J. Ventura, J. A. Ascacio-valdÉs, M. A. Cerqueira, D. B. Villa, J. C. Contreras-esquivel, Aguilar GonzÁlezM. A., A. ., and C. N. Aguilar. “MICROENCAPSULATION OF ELLAGIC ACID FROM POMEGRANATE HUSK AND KARAYA GUM BY SPRAY DRYING”. International Journal of Pharmacy and Pharmaceutical Sciences, Vol. 7, no. 13, Dec. 2015, pp. 212-6, https://innovareacademics.in/journals/index.php/ijpps/article/view/7053.