• Nikhil Yada Doctor of Pharmacy (Pharm. D), Department of Pharmacy Practice, Acharya and B. M Reddy College of Pharmacy, Bangalore, India 560107
  • Dhruva Teja Thrulapati Acharya and B. M Reddy College of Pharmacy
  • Arpit Maheshwari Acharya and B. M Reddy College of Pharmacy
  • Vihar Upadhyay Acharya and B. M Reddy College of Pharmacy
  • Pranit Shah Acharya and B. M Reddy College of Pharmacy


Objectives: There are many variations in prescribing patterns of Diabetes mellitus with hypertension which requires lifelong treatment as enormously increased the burden of chronic diseases and needs much care while choosing drugs. In a tertiary care Centre, prescribing pattern are powerful tools to ascertain the role of drugs in society. Hence, there is a need for appropriate, safe, effective and economical study to find out the patterns of drug therapy among diabetic hypertensive patients with other complications.

Methods: Retrospective, randomized and non-interventional study design was conducted from September 2014 to November 2014 at a Community Clinic in Telangana State. The collected data are thoroughly analyzed and prescriptions were checked for appropriateness. For easy sorting all data obtained were entered into Microsoft Excel 2000 and cross-checked for accuracy. The data collected were analyzed to obtain averages, percentages and standard deviations. The data were grouped on the bases of age, gender, fasting blood glucose, blood pressure, co morbidities, various classes of drugs and analyzed for significance.

Results: A total of 109 patients were included in this two months study. All the patients had Type 2 diabetes, while 18 patients also had Hypertension (on treatment). All the patients were on treatment for Type 2 Diabetes. The mean fasting Blood sugar was 119.27±40.34 mg/dl, while the mean post-prandial blood sugar was 212.78±67.35 mg/dl. The average number of OHAs per prescription was 1.99±0.54. About 19.26% of the patients were on monotherapy with Metformin, while all the other patients received a combination of oral hypoglycemic agents. Insulin was used in 2.75% of the patients. Among combinations, the most commonly used combination was glibenclamide and metformin 41.2%.

Conclusion: Metformin is the drug of choice and glibenclamide is the most preferred combination with Metformin. Insulin was not preferred as monotherapy. Despite combination therapy, the post-prandial glucose levels were not in range–suggesting either poor patient compliance or inadequate dosing/inappropriate therapy. In addition to drugs, the services of a clinical pharmacist might be helpful in these patients.


Keywords: Prescription Pattern, Diabetes Mellitus, Oral Hypoglycemic Agents, Community


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1. Anjana RM, Pradeepa R, Deepa M, Datta M, Sudha V, unnikrishnan R, et al. prevalence of diabetes and prediabetes (impaired fasting glucose and/or impaired glucose tolerance) in urban and rural india: phase I reults of the indian council of medical research-INdia DIABetes (ICMR-INDIAB) Study. Diabetologia 2011;54:3022-7.
2. International diabetes federation. IDF Diabetes Atlas. 5th ed. Brussels, Belgium: International Fedration; 2011. Available from: http://www.idf.org/diabetesatlas. [Last accessed on 2012 Jul 10].
3. Ramachandran A, Snehalatha C. Current scenario of diabetes in India. J Diabetes 2009;1:18-28.
4. Mehta SR, Kashyap AS, Das S. Diabetes mellitus in india: the modern scourge. MJAFI 2009;65:50-4.
5. The expert committee on the diagnosis and classification of diabetes mellitus. Report of the expert committee on the diagnosis and classifications of diabetes mellitus. Diabetes Care 1997;20:1183–97.
6. Davis SN. Insulin, oral hypoglycemic agents, and pharmacology of the endocrine pancreas. In: Brunton LL, Lazo JS, Parker KL. editors. Goodman and Gilman`s The Pharmacological Basis of Therapeutics. 11th ed. United States of America McGraw‑Hill; 2006. p. 1613-45.
7. Powers AC. Diabetes mellitus. In: Kasper DL, Braunwald E, Fauci AS, Hauser SL, Lango DL, Jameson JL. editors. Harrison`s Principles of Internal Medicine. 16th ed. New york McGraw‑Hill; 2005. p. 2152-80.
8. Tedesco MA, Natale F, Di Salvo G, Caputo S, Capasso M, Calabró R. Effects of coexisting hypertension and type II diabetes mellitus on arterial stiffness. J Hum Hypertens 2004;18:469-73.
9. Norman M. Kaplan, Treatment of coexisting diabetes and hypertension. Current Cardiology Reports Riddle M. Combining sulphonylureas and other oral agents. AMJ Med 2000;108:155-225.
10. Mukhopadhyay P, Paul B, Das D, Sengupta N, Majumder R. Perceptions and practices of type II diabetes: A cross-sectional study in tertiary care hospital in Kolkata. Int J Diabetes Dev Countries 2010;30:143-9.
11. Gul N. Knowledge, attitudes and practices of type 2 diabetic patients. J Ayub Med College 2010;22:128-31.
12. Ajayi IO, Arije A, Ekore JO, J Ekore RI. Attitude; diabetic foot care, education; knowledge; type 2 diabetes mellitus. Afr Health Care Fam Med; 2010. p. 2.
13. Vermeire E, Royen PV, Coenen S, Wens J, Denekens J. The adherence of type 2 diabetes patients to their therapeutic regimens: a qualitative study from the patient’s perspective. Practical Diabetes Int 2003;20:209-14.
14. Peyrot M, Rubin RR, Lauritzen T, Snoek FJ, Matthews DR, Skovlund SE. Psychosocial problems and barriers to improved diabetes management: results of the cross-national diabetes attitudes, Wishes and needs (DAWN) study. Diabetic Med: J Br Diabetic Assoc 2005;22:1379-85.
15. Hasamnis A, Patil S. Prescription pattern study in type 2 diabetesmellitus in an Indian referral hospital. Internet J Pharmacol 2009;7:1.
16. Truter I. An investigation into antidiabetic medication prescribing in South Africa. J Clin Pharm Ther 1998;23:417-22.
17. Adibe MO, Aguwa CN, Ukwe CV, Okonta JM, Udeogaranya PO. Outpatient utilization of anti-diabetic drugs in the South Eastern Nigeria. Int J Drug Dev Res 2009;1:27-36.
18. Rajeshwari S, Adikhari P, Pai MR. Drug utilisation study in geriatric type 2 diabetic patients. J Clin Diagn Res 2007;1:4403.
19. KA Al Khaja, RP Sequeira, VS Mathur. Prescribing patterns and therapeutic implications for diabetic hypertension in Bahrain. Ann Pharmacother 2001;35:1350-9.
20. Hermann LS, Schersten B, Bitzen PO, Kjellstrom T, Lindgarde F, Melander A. Therapeutics comparison of metformin and sulphonylurea alone and in combinations: a double blind controlled study. Diabetes Care 1994;17:1100–9.
21. Krentz AJ, Bailey CJ. Oral antidiabetic agents: current role in type 2 diabetes mellitus. Drugs 2005;65:385–411.
22. Riddle MC. Oral pharmacologic management of type 2 diabetes. Am Fam Physician 1999;60:2613–20.
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How to Cite
Yada, N., D. T. Thrulapati, A. Maheshwari, V. Upadhyay, and P. Shah. “A STUDY ON THE PRESCRIBING PATTERN OF ANTI-DIABETIC DRUGS IN A COMMUNITY CLINIC IN TELANGANA STATE”. International Journal of Pharmacy and Pharmaceutical Sciences, Vol. 7, no. 9, July 2015, pp. 222-6, https://innovareacademics.in/journals/index.php/ijpps/article/view/7431.
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