VECURONIUM AND CARDIAC ARREST

  • Bandya Sahoo Department of Pediatrics, Kalinga Institute of Medical Sciences, Bhubaneswar, Odisha, India

Abstract

Vecuronium is widely used to provide skeletal muscle relaxation in mechanically ventilated Intensive Care Unit patients. The absence of significant cardiovascular side-effects is one of its stated advantages. There have been isolated reports of Brady-dysrhythmias including sinus arrest and atrioventricular block when vecuronium was administered with other agents especially opioids. We report a case of cardiac arrest following administration of vecuronium alone in a mechanically ventilated child in the Intensive Care Unit.

Keywords: Vecuronium, Sinus arrest, Atrioventricular block.

Downloads

Download data is not yet available.

Author Biography

Bandya Sahoo, Department of Pediatrics, Kalinga Institute of Medical Sciences, Bhubaneswar, Odisha, India
Department of Pediatrics, Associate Professor

References

1. Booij LHDJ, Edwards RP, Sohn, YJ. Cardiovascular and neuromuscular effects of ORG NC45, pancuronium, metocurine and d-tubocurarine in dogs. Anesth Analg 1980;59:26-30.
2. May JR. Vecuronium and bradycardia. Anaesthesia 1985;40:410.
3. Kirkwood I, Duckworth RA. An unusual case of sinus arrest. Br J Anaesth 1983;55:1273.
4. Clayton D. Asystole associated with vecuronium. Br J Anaesth 1986;58:937-8.
5. Starr NJ, Sethna DH, Estafanous FG. Bradycardia and asystole following the rapid administration of sufentanil with vecuronium. Anesthesiology 1986;64:521-3.
6. Cozanitis DA, Erkola O. A clinical study into the possible intrinsic bradycardia activity of vecuronium. Anaesthesia 1989;44:648-50.
7. Inoue K, EI-Banayosy A, Stolarsky L. Vecuronium-induced bradycardia following induction of anaesthesia with etomidate and thiopentone with or without fentanyl. Br J Anaesth 1988;60:10-3.
8. Salmenpera M, Peltola K, Takkunen O. Cardiovascular effects of pancuronium and vecuronium during high-dose fentanyl anesthesia. Anesth Analg 1983;62:1059-64.
9. Cozanitis DA, Pouttu J, Rosenberg PH. Bradycardia associated with the use of vecuronium. A comparative study with pancuronium with and without glycopyrronium. Anaesthesia 1987;42:192-4.
10. Yeaton P, Teba L. Sinus node exit block following administration of vecuronium. Anaesthesia 1988;68:177-8.
Statistics
190 Views | 799 Downloads
How to Cite
Sahoo, B. “VECURONIUM AND CARDIAC ARREST”. International Journal of Pharmacy and Pharmaceutical Sciences, Vol. 8, no. 2, Feb. 2016, pp. 342-3, https://innovareacademics.in/journals/index.php/ijpps/article/view/9670.
Section
Case Study(s)