CHEMICAL COMPOSITION OF ESSENTIAL OILS AND ITS LOCOMOTOR ACTIVIT FROM THE BARKS OF Cinnamomum sintok Bl OF TWO DISTRICTS IN MIDDLE JAVA
Objective: The objective of this study was to determine of volatile compounds of essential oils from Cinnamomum sintoc B1 (sintok) barks belongs to Lauraceae of two Districts of Middle Java.
Methods: Analysis of essential oil components from the barks of Cinnamomum sintoc Bl was performed by confirmation of the linear retention index (LRI), following byÂ the comparison of Â NIST library peak and mass spectrum peak with literature data.
Results: The essential oils from Yogyakarta andÂ Jember of Cinnamomum sintoc Bl obtained by steam distillation with percentage of Â 1.10% and 1.15% (w/w), respectively, with eugenol and methyl eugenol having higher percentage compare to other components, 35-38% and less than 10%, respectively. The sintok barks oil of Yogyakarta at 0.1 mL a dose decreased the locomotor activity as much as 11.33 %, while at 0.3 and 0.5 mL doses increased the locomotor activity as much as 35.83 % and 51.13 %.
Conclusion: It can be concluded from this study that the inhalation of sintok barks oil gave different influence to locomotor activity depends on the doses given.
Keywords: Cinnamomum sintoc Bl, methyl eugeunol, LRI, and eugenol
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