• Muchtaridi Muchtaridi Department of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran
  • Sri Sumiw
  • Rina F Nuwarda


Objective: The objective of this study was to determine of volatile compounds of essential oils from Cinnamomum sintoc B1 (sintok) barks belongs to Lauraceae of two Districts of Middle Java.

Methods: Analysis of essential oil components from the barks of Cinnamomum sintoc Bl was performed by confirmation of the linear retention index (LRI), following by  the comparison of  NIST library peak and mass spectrum peak with literature data.

Results: The essential oils from Yogyakarta and  Jember of Cinnamomum sintoc Bl obtained by steam distillation with percentage of  1.10% and 1.15% (w/w), respectively, with eugenol and methyl eugenol having higher percentage compare to other components, 35-38% and less than 10%, respectively. The sintok barks oil of Yogyakarta at 0.1 mL a dose decreased the locomotor activity as much as 11.33 %, while at 0.3 and 0.5 mL doses increased the locomotor activity as much as 35.83 % and 51.13 %.

Conclusion: It can be concluded from this study that the inhalation of sintok barks oil gave different influence to locomotor activity depends on the doses given.

Keywords: Cinnamomum sintoc Bl, methyl eugeunol, LRI, and eugenol



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How to Cite
Muchtaridi, M., S. Sumiw, and R. F. Nuwarda. “CHEMICAL COMPOSITION OF ESSENTIAL OILS AND ITS LOCOMOTOR ACTIVIT FROM THE BARKS OF Cinnamomum Sintok Bl OF TWO DISTRICTS IN MIDDLE JAVA”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 10, no. 4, Apr. 2017, pp. 84-87, doi:10.22159/ajpcr.2017.v10i4.15780.
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