GREEN PHYTO-SYNTHESIS OF GOLD NANOPARTICLES USING ACHYRANTHES ASPERA LINN SEED-EPICOTYLS LAYER EXTRACTS AND ITS ANTICANCER ACTIVITY

Authors

  • ANAND M
  • SELVARAJ V
  • ALAGAR M
  • Ranjitha J

Abstract

In the recent past decades, green phyto-process for the synthesis of metal incorporated nanoparticles has been evolving into an imperative branch of nanotechnology. We have reported a rapid, expedient and extracellular method for the synthesis of gold nanoparticles by reducing gold chloride with the help of aqueous seed-epicotyls layer extracts of Achyranthes aspera Linn (Amarantheceae).  This approach is simple, economic, stable for a long time, reproducible at room temperature and is synthesized in an eco-friendly mode to obtain a self-assembly of gold nanoparticles (AuNPs).  The resulting gold nanoparticles were characterized using UV-Visible absorption spectroscopy, Scanning Electron Microscopy (SEM), X-ray Diffraction (XRD) and FT-IR spectroscopic techniques. The anticancer activity of the gold nanoparticles was studied against HeLa (Cervical) cancer cell lines. We herein report for the first time, Achyranthes aspera Seed-Epicotyls assisted synthesis of biogenic gold nanoparticles; the nanoparticles are conspicuously smaller and better faceted compared with those synthesized by A. aspera leaf extracts previously reported. Synthesized gold nanoparticles showed potent anticancer activity at 50μg/ml concentration against cervical cancer cell lines.

Keywords: Gold nanoparticles, anticancer activity, Achyranthes Aspera Linn.  Aqueous leaves Extract, SEM, XRD, HeLa cancer cell lines

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Published

2014-11-01

How to Cite

M, A., S. V, A. M, and R. J. “GREEN PHYTO-SYNTHESIS OF GOLD NANOPARTICLES USING ACHYRANTHES ASPERA LINN SEED-EPICOTYLS LAYER EXTRACTS AND ITS ANTICANCER ACTIVITY”. Asian Journal of Pharmaceutical and Clinical Research, vol. 7, no. 5, Nov. 2014, pp. 136-9, https://innovareacademics.in/journals/index.php/ajpcr/article/view/1696.

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