MAGNETIC MICROSPHERE AN EMERGING DRUG DELIVERY SYSTEM


Diksha Sharma, Abhishek Sharma

Abstract


 

 The drug delivery system has been advanced to release the drug according to the body requirement during the entire period of treatment and also for the delivery at the targeted site. Several novel drug delivery systems have emerged encompassing different route of administration to achieve controlled and targeted drug delivery, magnetic microsphere carrier being one of them. Magnetic microsphere is an alternative to traditional radiation methods. As the traditional radiation methods use highly penetrating radiation that is absorbed throughout the body and cause side effects hence its use is limited. Therefore, a safe and effective alternate is needed like magnetic microsphere. The excessive circulating drug particles are minimized by this delivery system. Moreover, the aim of specific targeting is to enhance the effectiveness of drug delivery and at the same time to lessen the toxicity and side effects. Magnetic carriers receive magnetic responses to a magnetic field from incorporated materials that are used for magnetic microsphere are chitosan, dextran, etc. One of the most utilized magnetic microspheres is serum albumine whether from human or other suitable animals. Drug release from the albumin microsphere can be controlled by various stabilization procedures. Overall, the targeted magnetic microsphere is much valuable novel drug delivery system for what more work have to be done. By knowing the importance of all this, the present paper reviews the mechanism, preparation, and applications of magnetic microspheres. As the targeted drug delivery system implies selective and effective localization of drug into the target at therapeutic concentrations with limited access to non-target sites. Magnetic microspheres hold great promises for reaching the goal of controlled and site-specific drug delivery.


Keywords


Magnetic microspheres, Targeted drug delivery, target sites, Body, Radiation , Efficiency, Toxicity, Reduce side effec

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About this article

Title

MAGNETIC MICROSPHERE AN EMERGING DRUG DELIVERY SYSTEM

Keywords

Magnetic microspheres, Targeted drug delivery, target sites, Body, Radiation , Efficiency, Toxicity, Reduce side effec

DOI

10.22159/ajpcr.2017.v10i6.17284

Date

01-06-2017

Additional Links

Manuscript Submission

Journal

Asian Journal of Pharmaceutical and Clinical Research
Vol 10 Issue 6 June 2017 Page: 54-58

Print ISSN

0974-2441

Online ISSN

2455-3891

Statistics

77 Views | 82 Downloads

Authors & Affiliations

Diksha Sharma
Department of Pharmacy, L. R. Institute of Pharmacy, Solan, Himachal Pradesh, India
India

Abhishek Sharma
Department of Pharmacy, L. R. Institute of Pharmacy, Solan, Himachal Pradesh, India
India


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