ANTIOXIDANT ACTIVITY OF LEAF EXTRACTS OF HEMIDESMUS INDICUS (L.) R.BR. (ASCLEPIADACEAE).


Abdul Kaffoor H, Muthuraj K, Arumugasamy K

Abstract


Objective: A number of Indian medicinal plants have been used for thousands of years in a traditional system of medicine. Hemidesmus indicus is an important member of the Asclepiadaceae family. It is an endemic to the southern Western Ghats, India. The aim of the study was to investigate the free radical scavenging activity of H. indicus.

Methods: The aqueous and methanol leaf extracts of H. indicus were assayed for radical scavenging activity, using the stable free radical 2,2-diphenyl- 1-picryl-hydrazyl-hydrate and 2,2’-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid).

Results: The results revealed that the IC50 values of aqueous extract of H. indicus were found to be higher than that of the other solvent extracts. The free radical scavenging activity of the plant extracts may be due to the presence of phytoconstituents.

Conclusion: In all the methods, the aqueous extract has exhibited the good scavenging activity and this arises that the plant has a potential antioxidant agent.


Keywords


Hemidesmus indicus, Asclepiadaceae, Antioxidant.

| PDF |

References


Paz A, Cerdeiras C, Fernadez MP, Ferreira J, Moyna F, Soubes P, et al. Screening of Uruguayan medicinal plants for antimicrobial activity. J Ethnopharmacol 1995;20:67-9.

Sohni YR, Kaimal P, Bhatt RM. The antiamoebic effect of a crude drug formulation of herbal extracts against Entamoeba histolytica in vitro and in vivo. J Ethnopharmacol 1995;45(1):43-52.

Janardhanan K, Gurumoorthi P, Pugalenthi M. Nutritional potential of five accessions of a South Indian tribal pulse, Mucuna pruriens var. Utilis: II. Investigations on total free phenolics, tannins, trypsin and chymotrypsin inhibitors, phytohaemagglutinins, and in vitro protein digestibility. J Trop Subtrop Agroecosyst 2003;1:141-52.

Siddhuraju P, Becker K, Makkar HP. Studies on the nutritional composition and antinutritional factors of three different germplasm seed materials of an underutilized tropical legume. Mucuna pruriens var. Utilis. J Agric Food Chem 2000;48(12):6048-60.

Vidyarthi LP. Role of forest in tribal life. In: Sinha SP, editor. Tribals and Foress. Ranchi, India: Bihar Tribal Research Institute; 1987. p. 323.

Rice-Evans CA, Miller NJ, Paganga G. Structure antioxidant activity relationships of flavonoids and phenolic acids. Free Radic Biol Med 1996;20(7):933-56.

Scalbert A, Williamson G. Dietary intake and bioavailability of polyphenols. J Nutr 2000;130 8S Suppl:2073-85.

Katalinic V, Milos M, Modun D, Music I, Boban M. Antioxidant effectiveness of selected wines in comparison with (+) - Catechin. Food Chem 2004;86:593-600.

Kaushik N, Singh BG, Tomar UK, Naik SN, Satya V, Bisla SS, et al. Regional and habitat variability in azadirachtin content of Indian neem (Azadirachta indica A Jusieu). Curr Sci 2007;92(10):1400-6.

Zahin M, Aqil F, Ahmad I. The in vitro antioxidant activity and total phenolic content of four Indian medicinal plants. Int J Pharm Pharm Sci 2011;3(1):238-42.

Blois MS. Antioxidant determinations by the use of a stable free radical. Nature 1958;29:1199-200.

Re R, Pellegrini N, Proteggente A, Pannala A, Yang M, Rice-Evans C. Antioxidant activity applying an improved ABTS radical cationdecolorization assay. Free Radic Biol Med 1999;26(9-10):1231-7.

Samydurai P, Thangapandian V. Antioxidant property and polyphenols evaluation of aqueous root extract of Decalepis hamiltonii Wight & Arn. Int Curr Pharm J 2012a;1:71-6.

Cotran RS, Kumar V, Collins T. Pathologic Basis of Disease. Philadelphia, PA; W.B. Saunders; 1999.

Houghton PJ, Hylands PJ, Mensah AY, Hensel A, Deters AM. In vitro tests and ethno pharmacological investigations: Wound healing as an example. J Ethnopharmacol 2005;100(1-2):100-7.

Srinivasahan V, Durairaj B. Antioxidant and free radical scavenging effect of Morinda citrifolia fruit extract. Int J Pharm Pharm Sci 2014;6(4):55-9.

Zheng W, Wang SY. Antioxidant activity and phenolic compounds in selected herbs. J Agric Food Chem 2001;49(11):5165-70.




About this article

Title

ANTIOXIDANT ACTIVITY OF LEAF EXTRACTS OF HEMIDESMUS INDICUS (L.) R.BR. (ASCLEPIADACEAE).

Keywords

Hemidesmus indicus, Asclepiadaceae, Antioxidant.

DOI

10.22159/ajpcr.2017.v10i6.17634

Date

01-06-2017

Additional Links

Manuscript Submission

Journal

Asian Journal of Pharmaceutical and Clinical Research
Vol 10 Issue 6 June 2017 Page: 200-202

Print ISSN

0974-2441

Online ISSN

2455-3891

Statistics

99 Views | 153 Downloads

Authors & Affiliations

Abdul Kaffoor H
Department of Botany, Kongunadu Arts and Science College (Autonomous), Coimbatore - 641 029, Tamil Nadu, India.
India

Muthuraj K
Department of Botany, Kongunadu Arts and Science College (Autonomous), Coimbatore - 641 029, Tamil Nadu, India.
India

Arumugasamy K
Department of Botany, Kongunadu Arts and Science College (Autonomous), Coimbatore - 641 029, Tamil Nadu, India.
India


Article Tools


Email this article (Login required)
Email the author (Login required)

Refbacks

  • There are currently no refbacks.