GAS CHROMATOGRAPHY 􀇧 MASS SPECTROMETRY ANALYSIS OF ESSENTIAL OIL COMPOSITION OF CLERODENDRUM SERRATUM L.: A TRADITIONAL PLANT OF INDIA

  • Raj Kumar Tiwari Department of Pharmacy, Sunder Deep Pharmacy College, Ghaziabad, Uttar Pradesh, India.
  • Udayabanu M Department of Pharmacy, Jaypee University of Information Technology, Waknaghat, Solan, Himachal Pradesh, India.
  • Silpi Chanda Department of Pharmacognosy, Faculty, NIET, Pharmacy Institute, Greater Noida, Uttar Pradesh, India

Abstract

Objective: Clerodendrum serratum (L.) belonging to family Verbenaceae, commonly known as Bharangi, is a popular plant across various communities of India. Gas chromatography-mass spectrometry (GC-MS) is a unique technique to prospect various volatile principles and semivolatile compounds.

Materials and Methods: The phytoconstituents present in the root of n-hexane extract were evaluated by GC-MS using Clarus 500 mass spectrometer.

Results and Discussions: A total of 15 constituents were identified and characterized from the roots of C. serratum L. All the 15 compounds were tabulated with their retention time, percentage peak area, molecular formula, molecular weight, and Chemical Abstracts Service number. Out of all the compounds, 60% comprises the oxygenated compounds. Compound hexadecanoic acid, methyl ester, and benzene, 1,3-bis(1,1-dimethylethyl) showed highest percentage about 6.5 and 74.9, respectively.

Conclusion: This study showed the presence of 15 compounds ranging from alkane, alkene as longest chain along with ester, aromatic and nonaromatic hydrocarbons.

Keywords: Clerodendrum serratum, Gas chromatography-mass spectrometry technique, Phytoconstituents, Volatile principles.

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Tiwari, R. K., U. M, and S. Chanda. “GAS CHROMATOGRAPHY ô€‡§ MASS SPECTROMETRY ANALYSIS OF ESSENTIAL OIL COMPOSITION OF CLERODENDRUM SERRATUM L.: A TRADITIONAL PLANT OF INDIA”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 10, no. 7, July 2017, pp. 226-9, doi:10.22159/ajpcr.2017.v10i7.18674.
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