PREVALENCE OF FUNGAL IN OPPORTUNISTIC INFECTION HIV TYPE-1 IN SUBURBAN, KADAPA

  • Gundala Obulesu Assistant Professor, Bharath University, Chennai, Tamil Nadu, India. kerala
  • Hanumanthapp Ar JJM Medical College, Davangere, Karnataka, India
  • Prabakar Reddy E Department of Biochemistry, Sri Lakshmi Narayana Institute of Medical Sciences, Puducherry, India

Abstract

Objective: Isolate fungal element causing in opportunistic infection of human immunodeficiency virus and correlated with CD4 cell counts.

Methods: Different samples are used and media: Sabouraud dextrose agar, using mycological methods such as potassium hydroxide, lactophenol cotton blue mount, India ink preparation, and Gram-staining.

Results: Both bacterial and fungal isolates were obtained from 8 cases. Pneumococci and Candida spp. were observed in 3 cases followed by Staphylococcus aureus and Aspergillus in 2 cases, Klebsiella pneumoniae and Geotrichum spp., Pneumococci and Penicillium spp., and Acinetobacter baumannii, and Cryptococcus spp. from 1 case each. Only fungal isolates were obtained from 6 cases of sputum samples. Candida spp. (50%) were predominant fungal isolate followed by Aspergillus spp. (33.33%) and Cryptococcus spp. (16.66%). Cryptococcus spp. was the predominant fungal isolate (66.6%) followed by Candida pseudotropicalis (Kefyr) in 16.66% (1/6) and Acinetobacter spp. was isolated from 16.66 % (1/6).

Conclusion: Respiratory infections were the predominant manifestations comprising chronic bronchitis, pneumonia, chronic obstructive pulmonary disease, and chronic cough. 66 individuals were with respiratory symptoms, of them 28 individuals had CD4 count 50-200/mm3, 22 had CD4 <50/mm3.

Keywords: Acquired immune deficiency syndrome, Human immunodeficiency virus, CD4.

Author Biography

Gundala Obulesu, Assistant Professor, Bharath University, Chennai, Tamil Nadu, India. kerala
Assistant Professor, Department of microbiology, keralamedical college,pallakad

References

1. Brooks GF, Carroll KC, Butel JS. Jawetz, melnick and adelberg. Review of Medical Microbiology. 22nd ed. Ch. 44. New York: McGraw Hill Professional; 2001. p. 521.
2. AIDS Epidemic Update-Joint United Nations Programme on HIV/AIDS (UNAIDS) and World Health Organization (WHO) “UNAIDS/09.36E/JC1700E, November; 2015. p. 7
3. Ananthanarayana R, Paniker CK. Human immunodeficiency virus: AIDS. Text Book of Microbiology. 7th ed. Ch. 62. Madras: Orient Long Man Publications; 2005. p. 592.
4. Arora A. Medical Microbiology. 1st ed. London: Academic Press; 2014. p. 42.
5. Mackie JT. Mackie and McCartney: Practical Medical Microbiology. 11thed. New Delhi: Elsevier; 2006. p. 126.
6. Mackie JT. Mackie and McCartney: Practical Medical Microbiology. 11thed. New Delhi: Elsevier; 2006. p. 380.
7. Mackie JT. Mackie and McCartney: Practical Medical Microbiology. 11thed. New Delhi: Elsevier; 2006. p. 169.
8. Mackie JT. Mackie and McCartney: Practical Medical Microbiology. 11thed. New Delhi: Elsevier; 2006. p. 5.
9. Arora R. Medical Mycology. 1sted. Philadelphia, PA: Lea and Febiger; 2014. p. 122.
10. Arora R. Medical Mycology. 1sted. Philadelphia, PA: Lea and Febiger; 2014. p. 128-129.
11. Arora R. Medical Mycology. 1sted. Philadelphia, PA: Lea and Febiger; 2014. p. 114-1115.
12. Arora R. Medical Mycology. 1sted. Philadelphia, PA: Lea and Febiger; 2014. p. 43-4.
13. Shailaja VV, Pai LA, Mathur DR, Lakshmi V. Prevalence of bacterial and fungal agents causing lower respiratory tract infections in patients with human immunodeficiency virus infection. Indian J Med Microbiol 2004;22(1):28-33.
14. Aggarwal A, Arora U, Bajaj R. Clinico-microbiological study in HIV seropositive patients. J Indian Acad Clin Med 2005;6(2):142-5.
15. Baradkar VP, Karyakarte RP. Isolation and characterization of Candida species in AIDS. Indian J Med Microbiol 1999;17(1):42-4.
16. Di Silverio A, Brazzelli V. Prevalence of dermatophytes and yeasts (Candida Spp., Malassezia furfur) in HIV patients. Mycopathologia 2004;114:103-7.
17. Arora A. Medical Microbiology. 1st ed. UK: Oxford University Press; 2014. p. 111.
18. Currie BP, Casadevall A. Estimation of the prevalence of cryptococcal infection among patients infected with the HIV in New York city. Clinical Infection 1994;9(6):1029-33.
19. Yehia AG. Treatment of tenia versicolor caused by Malassezia furfur with dill seed extract. Int J Pharm Pharm Sci 2015;7(2):1-7.
20. Medeios CS. Activity anti-C, Tropicalis and effect of the combination of(s)-(s) citronellal with four antifungal applied in vulvoveginal candidiasis. Int J Pharm Pharm Sci 2016;8(8):347-51.
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Obulesu, G., H. Ar, and P. R. E. “PREVALENCE OF FUNGAL IN OPPORTUNISTIC INFECTION HIV TYPE-1 IN SUBURBAN, KADAPA”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 10, no. 6, June 2017, pp. 403-5, doi:10.22159/ajpcr.2017.v10i6.19404.
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