ULTRAVIOLET SPECTROSCOPY AND ITS PHARMACEUTICAL APPLICATIONS- A BRIEF REVIEW


Dipali M Atole, Hrishikesh H Rajput

Abstract


 Rapid and easy analytical methods are needed due to increasing number of multicomponent formulations, biotherapeutic products and samples of complex matrix in que. Number of Ultraviolet (UV) spectrophotometric methods used for these purpose. Different types of UV spectrometric methods developed on the basis of principle of additivity, absorbance difference, processing absorption spectra. The aim of this review is to present information on simultaneous equation method, difference spectrophotometry, derivative spectrophotometry, absorbance ratio spectra, derivative ratio spectra, successive ratio - derivative spectra, Q-absorbance ratio method, absorptivity factor method, dual wavelength method, absorption factor method, multivariate chemometric methods, and isosbestic point method. A brief summary on theories, mathematical background and some applications of these methods are presented here.


Keywords


Ultraviolet spectroscopy, Simultaneous equation method, Derivative spectrophotometry, Derivative ratio spectra, Isosbestic point method, Multivariate chemometric methods.

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About this article

Title

ULTRAVIOLET SPECTROSCOPY AND ITS PHARMACEUTICAL APPLICATIONS- A BRIEF REVIEW

Topics

PHARMACEUTICAL ANALYSIS

Keywords

Ultraviolet spectroscopy, Simultaneous equation method, Derivative spectrophotometry, Derivative ratio spectra, Isosbestic point method, Multivariate chemometric methods.

DOI

10.22159/ajpcr.2018.v11i2.21361

Date

01-02-2018

Additional Links

Manuscript Submission

Journal

Asian Journal of Pharmaceutical and Clinical Research
Vol 11 Issue 2 February 2018 Page: 59-66

Print ISSN

0974-2441

Online ISSN

2455-3891

Statistics

224 Views | 244 Downloads

Authors & Affiliations

Dipali M Atole
Department of Pharmaceutics, Government College of Pharmacy, Aurangabad, Maharashtra, India
India

Hrishikesh H Rajput
Department of Pharmaceutics, Government College of Pharmacy, Aurangabad, Maharashtra, India
India


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