CHEMICAL HAZARDS IN PHARMACEUTICAL INDUSTRY: AN OVERVIEW


Princy Agarwal, Anju Goyal, Rajat Vaishnav

Abstract


 The pharmaceutical industry is a vital component of health-care systems all over the world engaged in discovery, development, manufacture, and marketing of medicines for human as well as animal health. Pharmaceutical industries also have many environmental problems, like the other chemical industries. The pharmaceutical industry is based primarily on the scientific formulation, research, and development of drugs, that is, helpful in the prevention or treatment of diseases and disorders. The manufacturing of APIs and formulation processes involves the use of various chemicals which includes various corrosive and irritant agents such as acids, bases, oxidizing and reducing agents, solvents, and many more which can be found sometimes at very high concentrations and are hazardous to health of persons performing the various processes during manufacturing and formulation of API and medicines. The effective management of the chemical risks linked to the handling of these agents is mandatory for the safety of the workers in the industry, ethically and also legally as per the rules and guidelines of various acts regulating the functioning of the pharma industry. This article provides a comprehensive review of various chemical hazards generally encountered by the pharmaceutical industry, its management and regulation in India.


Keywords


Chemical hazards, Industrial hazard, Organic solvent, Hazardous gases, Organic synthesis, Management of hazard, Regulations for chemical hazard, Regulatory agencies for hazards, Workplace safety, Threshold limit value.

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About this article

Title

CHEMICAL HAZARDS IN PHARMACEUTICAL INDUSTRY: AN OVERVIEW

Keywords

Chemical hazards, Industrial hazard, Organic solvent, Hazardous gases, Organic synthesis, Management of hazard, Regulations for chemical hazard, Regulatory agencies for hazards, Workplace safety, Threshold limit value.

DOI

10.22159/ajpcr.2018.v11i2.23160

Date

01-02-2018

Additional Links

Manuscript Submission

Journal

Asian Journal of Pharmaceutical and Clinical Research
Vol 11 Issue 2 February 2018 Page: 27-35

Print ISSN

0974-2441

Online ISSN

2455-3891

Statistics

73 Views | 87 Downloads

Authors & Affiliations

Princy Agarwal
Department of Quality Assurance, Bhupal Nobles Institute of Pharmaceutical Sciences, Sevashram Road, Udaipur, Rajasthan, India
India

Anju Goyal
Department of Quality Assurance, Bhupal Nobles Institute of Pharmaceutical Sciences, Sevashram Road, Udaipur, Rajasthan, India
India

Rajat Vaishnav
Department of Quality Assurance, Bhupal Nobles Institute of Pharmaceutical Sciences, Sevashram Road, Udaipur, Rajasthan, India
India


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