EFFECT OF SLEEP DEPRIVATION ON REMINISCENCE AND APPREHENSION BEHAVIOR IN WISTAR ALBINO RATS

  • KEERTHI PRIYA CS Department of Physiology, Dr. ALM Post Graduate Institute of Basic Medical Sciences, University of Madras, Chennai, Tamil Nadu, India.
  • MALATHI S Department of Physiology, Madha Medical College and Hospital, Kovur, Thandalam, Chennai, Tamil Nadu, India. https://orcid.org/0000-0001-7769-3624
  • RAVINDRAN RAJAN Department of Physiology, Dr. ALM Post Graduate Institute of Basic Medical Sciences, University of Madras, Chennai, Tamil Nadu, India.

Abstract

Objective: The aim of the present study is to investigate the effect of paradoxical sleep deprivation (SD) on learning and memory impairment and anxiety-like behavior in female Wistar albino rats.


Methods: Eight-arm radial maze, open-field test, and light and dark test were used to assess the animals learning and memory and anxiety-like behavior.


Results: SD associated with weaker learning and memory and increased anxiety- and depressive-like behavior in animals.


Conclusion: Animals were exposed to SD showed learning and memory impairment and also exhibited increased anxiety- and depressive-like behavior when compared to control animals.

Keywords: Behavior, Sleep deprivation, Cognition

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PRIYA CS, K., M. S, and R. RAJAN. “EFFECT OF SLEEP DEPRIVATION ON REMINISCENCE AND APPREHENSION BEHAVIOR IN WISTAR ALBINO RATS”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 13, no. 1, Nov. 2019, pp. 196-01, doi:10.22159/ajpcr.2020.v13i1.35187.
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