CLINICAL TRIALS: PERSPECTIVES OF MEDICAL COMMUNITY

  • HARI SANKAR KN Department of Pharmacology, Government Medical College, Kottayam, Kerala, India.
  • DHANYA SASIDHARAN PALAPPALLIL Department of Pharmacology, Government Medical College, Kottayam, Kerala, India. https://orcid.org/0000-0001-5476-6229
  • PRABITHA PANATTIL Department of Pharmacology, Government Medical College, Kottayam, Kerala, India.

Abstract

Objective: The objective of the study was to determine the knowledge, attitude, and perception about clinical trials (CTs) among medical community of a tertiary care institution.


Methodology: This was a questionnaire-based cross-sectional study conducted in the Department of Pharmacology, Government Medical College in Central Kerala for a period of 1 year. In a sample population of 690 comprising medical undergraduates (3rd phase), residents, and doctors in Medical Education Service (MES), 309 questionnaires were distributed randomly assuming 80% response to achieve the sample size of 247. Knowledge, attitude, and perceptions were quantified with a cumulative score with a scoring scheme of +1 for a correct response/positive attitude/positive perception and 0 for an incorrect response/no response/negative attitude/negative perception. The data were analyzed using SPSS 16, the knowledge, attitude, and perception were expressed as mean score as well as proportion.


Results: The response rate was 95.79%. Of the 296 completed responses, 158 (53.4%) were from medical undergraduates, 62 (20.9%) from residents, and 76 (25.7%) from doctors in MES. The mean knowledge was 14.8±3.79 (maximum score 25). The mean attitudinal score was 7.07±1.82 (maximum score 10). The mean score of the participants on perception (maximum score=10) about CTs conducted in India was 4.11±2.02 which denoted a negative perception.


Conclusion: The participants had good knowledge and positive attitude about CTs, however, all the three groups of participants had negative perception about CTs currently conducted in India.

Keywords: Clinical trial, Knowledge, Attitude, Perception, Questionnaire

Author Biographies

HARI SANKAR KN, Department of Pharmacology, Government Medical College, Kottayam, Kerala, India.

Assistant Professor, Pharmacology

Government Medical College,Kottayam, Kerala

DHANYA SASIDHARAN PALAPPALLIL, Department of Pharmacology, Government Medical College, Kottayam, Kerala, India.

Associate Professor(Career Advancement Promotion)

Department of Pharmacology

Government Medical College, Kottayam

PRABITHA PANATTIL, Department of Pharmacology, Government Medical College, Kottayam, Kerala, India.

Assistant Professor, Department of Pharmacology

Government Medical College, Kottayam

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SANKAR KN, H., D. S. PALAPPALLIL, and P. PANATTIL. “CLINICAL TRIALS: PERSPECTIVES OF MEDICAL COMMUNITY”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 13, no. 9, June 2020, pp. 44-48, doi:10.22159/ajpcr.2020.v13i9.38228.
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