EVALUATION OF RATIONAL USE OF ANTIBIOTIC DRUGS IN SURGERY DEPARTMENT AT A TERTIARY CARE HOSPITAL
Objective: Antibiotics are the only drug where use in one patient can impact the effectiveness in another, so antibiotic misuse adversely impacts the patients and society. Improving antibiotic use improves patient outcomes and saves money. Antibiotic resistance has been identified as a major threat by the WHO due to the lack of development of new antibiotics and the increasing infections caused by multidrug resistance pathogens became untreatable.
Methods: A prospective observational study was conducted for a period of 6 months. Data were collected from prescriptions and inpatient record files at the surgery department of the tertiary care hospital. Patients above age of 18 years of either gender whose prescription containing the antibiotics and patients who are willing to participate in the study were included in the study. Microsoft Excel was used for recording and analyzing the data of recruited subjects.
Results: During our study period, we have collected 100 cases as per inclusion criteria, in total collected 100 cases, 52% are male and 48% are female. The mean age and standard deviation of the study population were found to be 46.61±16.12. The most commonly prescribed classification before and after the surgery is cephalosporin’s that is 57%. Results show that in pre-surgery, almost 93% of prescriptions have chosen the drugs as per ASHP guidelines, whereas in post-surgery, 95% of drugs have selected the drug as per ASHP guidelines.
Conclusion: Our study has observed that some of the prescriptions are irrationally prescribed so the pharmacist has to take the responsibility to improve the awareness regarding rational prescribing of antibiotics. The national wide monitoring of antibiotics use, national schemes to obtain rational use of antibiotics, reassessing the prescriptions, education to practitioners, and surveys on antibiotics should be implemented.
2. Kourkouta L, Kotsiftpoulos CH, Papageorgiou M, Iliadis CH, Monios A. The rational use of antibiotics medicine. J Healthc Commun 2017;2:1-4.
3. Kathleen AH. Promoting the rational use of antibiotics. Reg Health Forum 2011;15:122-30.
4. Salih C, Ali PD. Antibiotics and the mechanism of resistance to Antibiotics. Med J Islam World Acad Sci 2013;21:138-42.
5. Prashant D, Prakash G, Subodh U. A comparative study for the role of preoperative antibiotics prophylaxis in the prevention of surgical site infections. IOSR J Pharm 2014;13:27-31.
6. Alemkere G. Antibiotic usage in surgical prophylaxis: A prospective observational study in the surgical ward of Nekemte referral hospital. PLoS One 2018;13:e0203523.
7. SIGN Antibiotic Prophylaxis in Surgery. A National Clinical Guideline; 2008. p. 1-71. Available from: http://www.just.edu.jo/ar/dic/guidelines.
8. Shukry Z, Chathurangani H, Hana M. Assessing knowledge, perception and attitudes about antibiotics among final year pharmacy undergraduates in Sri Lanka. Int J Pharm Pharm Sci 2017;9:234-9.
9. Sumon KD, Tripti RP, Monalisa M, Ambia K, Rafiqul I, Ali A, et al. Patterns of prescription and antibiotic use among outpatients in a tertiary care teaching hospital of Bangladesh. Int J Pharm Pharm Sci 2016;8:60-3.
10. Suman L, Vijay K, Vineeta S, Sanjay S. Prescribing pattern of antibiotics among outdoor patient in medicine department of tertiary care hospital in Northern India. Int J Pharm Pharm Sci 2020;12:43-6.
This work is licensed under a Creative Commons Attribution 4.0 International License.
The publication is licensed under CC By and is open access. Copyright is with author and allowed to retain publishing rights without restrictions.