ACUTE SUICIDAL POISONING BY ALUMINUM PHOSPHIDE: RARE CASE REPORT FROM NORTHERN RURAL INDIA

Authors

  • KANIKA KOHLI Department of Forensic Medicine, Maharishi Markandeshwar Institute of Medical Sciences and Research, Maharishi Markandeshwar Deemed to be University, Mullana, Haryana, India.
  • RANJODH JEET SINGH Department of Pharmacology, Maharishi Markandeshwar Institute of Medical Sciences and Research, Maharishi Markandeshwar Deemed to be University, Mullana, Haryana, India.
  • SONIA KOCHHAR Department of Physiology, All India Institute of Medical Sciences, Bathinda, Punjab, India.

DOI:

https://doi.org/10.22159/ajpcr.2021.v14i8.42193

Keywords:

fd

Abstract

Aluminum phosphide (ALP) is a highly toxic pesticide and is lethal if abused as a suicidal agent invariably. The ALP or a celphos powder is a major contributor to mortality, as such celphos poisoning lacks a specific antidote. The management of the patients includes fast decontamination and all international protocol supportive measures. The ALP poisoning has gained enormous interest with the spike in the number of cases due to its increased use for non-agricultural purposes as well. The easy ease of availability and laxity in the implementation of the sale of pesticides has eventually led to misuse, rather an abuse for the commitment of suicide. Celphos powder is commonly available in the form of tablets. This is a case of suicidal consumption of ALP by 54 years old male, a farmer by occupation. According to our interpretation, we believe that strict implementation of pesticide laws must be enforced and suicide help awareness programs under the banner of government and non-government organizations must come in the front line up.

Downloads

Download data is not yet available.

References

Kumar A, Pathak A, Verma A, Kumar S. Accidental inhalational poisoning by multiple pesticides of the organophosphorus group in an ages person: An uncommon occurrence. J Forensic Med Toxicol 2012;29:78-83.

Mehrpour O, Amouzeshi A, Dadpour B, Oghabian Z, Zamani N, Amini S, et al. Successful treatment of cardiogenic shock with an intraaortic balloon pump following aluminum phosphide poisoning. Arch Ind Hyg Toxicol 2014;65:121-7.

Soltaninejad K, Nelson LS, Bahreini SA, Shadnia S. Fatal aluminum phosphide poisoning in Tehran-Iran from 2007 to 2010. Indian J Med Sci 2012;66:66-70.

Bogle RG, Theron P, Brooks P, Dargan PI, Redhead J. Aluminium phosphide poisoning. Emerg Med J 2006;23:e03.

Meena HS, Murthy OP, Bose S, Bhatia S, Dogra TD. Aluminum phosphide poisoning. J Forensic Med Toxicol 1989;11:19-30.

Jeyaratnam J. Acute pesticide poisoning: A major global health problem. World Health Stat Q 1990;43:139-44.

Lauterbach M, Solak E, Kaes J, Wiechelt J, Von Mach MA, Weilemann LS. Epidemiology of hydrogen phosphide exposures in humans reported to the poison center in Mainz, Germany, 1983-2003. Clin Toxicol (Philia) 2005;43:575-81.

Price NR, Moles KA, Humphires OA. Phosphine toxicity and catalase activity in susceptible and resistant strains of lesser grain borer (Rhyzopertha dominica). Comp Biochem Physiol 1982;73:411-5.

Chugh SN, Arora V, Sharma A, Chugh K. Free radical scavengers and lipid peroxidation in acute aluminum phosphide poisoning. Indian J Med Res 1996;104:190-3.

Dua R, Gill KD. Aluminum phosphide exposure: Implications on rat brain lipid peroxidation and antioxidant defense system. Pharmacol Toxicol 2001;89:315-9.

Proudfoot AT. Aluminum and zinc phosphide poisoning. Clin Toxicol (Philia) 2009;47:89-100.

Gurjar M, Baronia AK, Azim A, Sharma K. Managing aluminum phosphide poisonings. J Emerg Trauma Shock 2011;4:378-84.

Singh RB, Singh RG, Singh U. Hypermagnesemia following aluminum phosphide poisoning. Int J Clin Pharmacol Ther Toxicol 1991;29:82-5.

Chugh SN, Dushyant, Ram S, Arora B, Malhotra KC. Incidence and outcome of aluminum phosphide poisoning in a hospital study. Indian J Med Res 1991;94:232-5.

Chhina RS, Thukral R, Chawla LS. Aluminum phosphide-induced gastroduodenitis. Gastrointest Endosc 1992;38:635-6.

Nijhawan S, Rastogi M, Tandon M, Mathur A, Rai RR. Aluminum phosphide induced esophageal stricture: an unusual complication. Endoscopy 2006;38 Suppl 2:E23.

Talukdar R, Singal DK, Tandon RK. Aluminum phosphide induced esophageal stricture. Indian J Gastroenterol 2006;25:98-9.

Madan K, Chalamalasetty SB, Sharma M, Makharia G. Corrosive-like strictures caused by ingestion of aluminum phosphide. Natl Med J India 2006;19:313-4.

Mehrpour O, Shadnia S, Soltannejad K, Yaghmaei A. Evaluation of electrolytes and blood glucose level in aluminum phosphide poisoning. Sci J Forensic Med 2009;15:49-53.

Shadnia S, Soltaninejad K, Hassanian-Moghadam H, Sadeghi A, Rahimzadeh H, Zamani N, et al. Methemoglobinemia in aluminum phosphide poisoning. Hum Exp Toxicol 2011;30:250-3.

Mostafazadeh B, Pajoumand A, Farzaneh E, Aghabiklooei A, Rasouli MR. Blood levels of methemoglobin in patients with aluminum phosphide poisoning and its correlation with patient’s outcome. J Med Toxicol 2011;7:40-3.

Published

07-08-2021

How to Cite

KOHLI, K., R. J. SINGH, and S. KOCHHAR. “ACUTE SUICIDAL POISONING BY ALUMINUM PHOSPHIDE: RARE CASE REPORT FROM NORTHERN RURAL INDIA”. Asian Journal of Pharmaceutical and Clinical Research, vol. 14, no. 8, Aug. 2021, pp. 1-2, doi:10.22159/ajpcr.2021.v14i8.42193.

Issue

Section

Case Study(s)