FREE RADICAL SCAVENGING AND NOS ACTIVATION PROPERTIES OF WATER SOLUBLE CRUDE POLYSACCHARIDE FROM PLEUROTUS OSTREATUS

Authors

  • PAYEL MITRA
  • SOMANJANA KHATUA
  • KRISHNENDU ACHARYA Molecular and Applied Mycology and Plant Pathology LaboratoryDepartment of BotanyUniversity of Calcutta35, Ballygunge Circular RoadKolkata, 700019West Bengal (India)

Abstract

The aim of this study was to investigate the antioxidant activity using different in vitro assays and nitric oxide synthase activation property of crude water soluble polysaccharide from P. ostreatus. The polysaccharide was isolated by hot water extraction and physico-chemical investigation revealed that it contained high amount of carbohydrate (mostly β-glucan) and low amount of protein and phenolic compounds. EC50 values for scavenging of hydroxyl radical and superoxide radical as well as chelating ability of ferrous ion were 665, 390 and 370 µg/ml respectively. The polysaccharide also showed potential nitric oxide synthase activation properties. This mushroom might be a good source of bioactive compounds.

Author Biography

KRISHNENDU ACHARYA, Molecular and Applied Mycology and Plant Pathology LaboratoryDepartment of BotanyUniversity of Calcutta35, Ballygunge Circular RoadKolkata, 700019West Bengal (India)

Molecular and Applied Mycology and Plant Pathology LaboratoryDepartment of Botany

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Published

2013-07-01

How to Cite

MITRA, P., S. KHATUA, and K. ACHARYA. “FREE RADICAL SCAVENGING AND NOS ACTIVATION PROPERTIES OF WATER SOLUBLE CRUDE POLYSACCHARIDE FROM PLEUROTUS OSTREATUS”. Asian Journal of Pharmaceutical and Clinical Research, vol. 6, no. 3, July 2013, pp. 67-70, https://innovareacademics.in/journals/index.php/ajpcr/article/view/53.

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