• Ratikanta Tripathy Assistant Professor, Dept. of Pharmacology, KIMS, BBSR, 751024
  • Jatin Kumar Majhi


Valproate is one of the most prescribed anti-epileptic drugs. It could cause a rise in serum ammonia level in patients, especially children and young
adults. This presents with altered orientation, lethargy, focal neurological deficit, etc. If this condition is not treated, then it can be fatal. There is a good
correlation between fall of ammonia level and clinical improvement. We, here, present a case of valproate induced hyperammonemia and deranged
liver function in a child of 1-year age admitted to a tertiary care hospital.
Keywords: Hyperammonemia, Hyperammonemic encephalopathy, Valproate.

Author Biography

Ratikanta Tripathy, Assistant Professor, Dept. of Pharmacology, KIMS, BBSR, 751024
Assistant Professor, Dept. of Pharmacology


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How to Cite
Tripathy, R., and J. K. Majhi. “VALPROATE INDUCED HYPERAMMONEMIAWITH DERANGED LIVER FUNCTION”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 8, no. 4, July 2015, pp. 1-2,
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