DRUG UTILIZATION STUDY IN OPHTHALMOLOGY OUTPATIENT DEPARTMENT IN A TERTIARY CARE TEACHING HOSPITAL OF WESTERN UTTAR PRADESH, INDIA

Authors

  • AMIT KUMAR JAIN
  • Seema Jain
  • Vikrant Sharma
  • Dadan Ji Pandey
  • Anand Shukla

Abstract

Objectives: Assessment of drug use pattern especially in developing countries is becoming increasingly necessary to promote the rational use of
drugs. The present study was done to investigate the drug utilization pattern in Ophthalmology Outpatient Department (OPD) at Saraswathi Institute
of Medical Sciences, Hapur, India, using the World Health Organization (WHO) drug use indicators.
Methods: The prescriptions of 1000 outpatients were included and analyzed using a predesigned form to record information from the OPD prescription
cards of each patient. Following WHO drug use indicators and additional indices were analyzed: Average number of drugs per prescription, number
of encounters with antibiotics, percentage of encounters with injections, percentage of drugs prescribed by their generic names, percentage of drugs
prescribed from the National Essential Drug List (NEDL), etc.
Results: Prescription analysis showed that the average number of drugs per prescription was 2.92. The drugs were prescribed in the form of eye drops
(53.08%), followed by ointments (22.43%), tablets (18.49%), and capsules (5.99%). The dosage form was indicated for all of the drugs prescribed, the
frequency of drug administration for 97.5% of the drugs, and the duration of treatment for 82.5% of the drugs prescribed. Antimicrobial agents were
the most commonly prescribed drugs followed by lubricants, anti-inflammatory, antiallergic, antiglaucoma drugs, etc. Percentage of drugs prescribed
by generic name and from NEDL was 1.19% and 24.45%, respectively. Patient's knowledge of correct dosage was 95%.
Conclusion: The prescription writing errors were less, however, there was very low generic prescribing and inadequate information about the
duration of therapy in many prescriptions.
Keywords: Drug utilization, Ophthalmology, World Health Organization, Generic name.

Downloads

Download data is not yet available.

References

REFERENCES

Hawkey CJ, Hodgson S, Norman A, Daneshmend TK, Garner ST. Effect

of reactive pharmacy intervention on quality of hospital prescribing.

BMJ 1990;300(6703):986-90.

Shalini S, Ravichandran V, Mohanty BK, Dhanaraj SK, Saraswathi R.

Drug utilization studies-an overview. Int J Pharm Sci Nanotehnol

;3:803-10.

Prajwal P, Rai M, Kumar KS, Bhat US, Dsouza FV. Drug utilization

pattern in ophthalmology department at a tertiary care hospital. Int Res

J Pharm 2013;4:205-10.

The Pursuit of Responsible use of Medicines: Sharing and Learning

from Country Experiences. Available from: http://www.apps.who.int/

iris/bitstream/10665/75828/1/WHO_EMP_MAR_2012.3_eng.pdf.

Baksaas I, Lunde PK. National drug policies: The need for drug

utilization studies. Trends Pharmacol Sci 1986;7:331-4.

Nehru M, Kohli K, Kapoor B, Sadhotra P, Chopra V, Sharma R.

Drug utilization study in out-patient ophthalmology department of

Government Medical College Jammu. JK Sci 2005;7(3):149-51.

Jain VK, Shrivastava B, Agarwal M. Drug utilization pattern of drugs

used along ophthalmic antiallergics formulations used in patients

diagnosed with seasonal and perennial allergic conjunctivitis. Asian J

Pharm Sci Res 2011;1:15-20.

The selection of essential drugs. Report of a WHO expert Committee.

World Health Organ Tech Rep Ser 1977;(615):1-36.

Reddy DC, Gupta VM. Rational use of Drugs: Problems in Indian

Context. Background Material for Workshop on Rational Drug Use.

Varanasi, Department of Preventive and Social Medicine, Institute of

Medical Sciences. Banaras Hindu University; 2001. p. 347-489.

World Health Organization and International Network for Rational Use

of Drugs. How to Investigate Drug Use in Health Facilities: Selected

Drug Use Indicators, WHO/DAP/93.1. Vol. 1. Geneva, Switzerland:

WHO; 1993. p. 1-87.

Biswas NR, Jindal S, Siddiquei MM, Maini R. Patterns of prescription

and drug use in ophthalmology in a tertiary hospital in Delhi. Br J Clin

Pharmacol 2001;51(3):267-9.

Sjoqvist F, Birkett D. Drug utilization. In: Bramley DW, editor.

Introduction to Drug Utilization Research. (WHO Booklet). New York:

WHO Office of Publication; 2003. p. 76-84.

Hogerzeil HV. Promoting rational prescribing: An international

perspective. Br J Clin Pharmacol 1995;39(1):1-6.

Maniyar Y, Bhixavatimath P, Akkone V. A drug utilization study in the

ophthalmology department of a Medical College, Karnataka, India.

J Clin Diagn Res 2011;5:82-4.

Banjara SK, Mudavath K, Bhukya KD. Pattern of prescription and drug

use in ophthalmology out-patient department in a teaching hospital.

Glob J Res Anal 2014;3:92-3.

Hasmnis AA, Patil SS, Narayan KA, Rashid AK, Mohanty BK. Drug

utilization study for acute illnesses in village Banggol, Malaysia; the

findings of a household survey. Al Ameen J Med Sci 2010;3:165-8.

Lee D, Bergman U. Studies of drug utilization. In: Storm BL, editors.

Pharmacoepidemiology. Chichester, UK: John Wiley & Sons; 2005.

p. 401-17.

Jadhav PR, Moghe VV, Deshmukh YA. Drug utilization study in

ophthalmology outpatients at a tertiary care teaching hospital. ISRN

Pharmacol 2013;2013:768792.

Krishnaswamy K, Kumar BD, Radhaiah G. A drug survey – precepts

and practices. Eur J Clin Pharmacol 1985;29(3):363-70.

Rambhade S, Chakarborty A, Shrivastava A, Patil UK, Rambhade A.

A survey on polypharmacy and use of inappropriate medications.

Toxicol Int 2012;19(1):68-73.

Nolan L, O’Malley K. Prescribing for the elderly. Part I: Sensitivity of the

elderly to adverse drug reactions. J Am Geriatr Soc 1988;36(2):142-9.

Sharma D, Reeta K, Badyal DK, Garg SK, Bhargava VK. Antimicrobial

prescribing pattern in an Indian tertiary hospital. Indian J Physiol

Pharmacol 1998;42(4):533-7.

Gangwar A, Singh R, Singh S, Sharma BD. Pharmacoepidemiology of

drugs utilized in ophthalmic outpatient and inpatient department of a

tertiary care hospital. J Appl Pharm Sci 2011;1;135-40.

Published

01-01-2016

How to Cite

JAIN, A. K. ., S. Jain, V. Sharma, D. J. Pandey, and A. Shukla. “DRUG UTILIZATION STUDY IN OPHTHALMOLOGY OUTPATIENT DEPARTMENT IN A TERTIARY CARE TEACHING HOSPITAL OF WESTERN UTTAR PRADESH, INDIA”. Asian Journal of Pharmaceutical and Clinical Research, vol. 9, no. 1, Jan. 2016, pp. 354-6, https://journals.innovareacademics.in/index.php/ajpcr/article/view/9997.

Issue

Section

Original Article(s)