COST-EFFECTIVENESS ANALYSIS ON THE USE OF PARENTERAL NUTRITION WITH D10-CA GLUCONATE AND D5 1/4NS IN NORMAL-WEIGHT NEONATES WITH RESPIRATORY DISTRESS SYNDROME

  • Fitria Ningsih 1Department of Pharmacy, Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia.
  • Rani Sauriasari 2Department of Apothecary, Kambang General Hospital, Jambi, Indonesia.
  • Agusdini Banun Saptaningsih Directorate General of Pharmaceutical Services and Medical Devices, Ministry of Health, Indonesia.

Abstract

Objectives: This retrospective cohort study aimed to compare the cost-effectiveness of using D10-CaGluconate and D5 1/4NS preparations in normalweight
neonatal patients with Respiratory Distress Syndrome (RDS) in Kambang General Hospital, Jambi, Indonesia.
Methods: The research was conducted from September 2014 to June 2015. The study participants were divided into two groups; D10-CaGluconate
was administered to 40 patients and D5 1/4NS to 43 patients. Effectiveness was assessed based on the changes in the physical examination results,
average weight gain (28.48 and 23.49 g/day), blood glucose levels (26.73 and 26.42 mg/dL), respiratory rate (−12.35 breaths/minute and −7.77
breaths/minute), pulse frequency (−10.98 and −8.07 ±), and body temperature (0.013°C and 0.012°C) of the patients in the D10-CaGluconate and
D5 1/4NS groups, respectively.
Results: The average direct medical costs of using D10-CaGluconate and D5 1/4NS were 458,290 IDR and 408,347 IDR, respectively. The average costeffectiveness
ratio value of total direct medical costs for D10-CaGluconate preparation was 35,207,467 IDR while that for D5 1/4NS was 33,958,602
IDR. The direct medical cost of the incremental cost-effectiveness ratio mean value of the D5 1/4NS preparation that compared to the D10-CaGluconate
preparation was 10,017,210 IDR.
Conclusions: The parenteral nutrition preparation of D10-CaGluconate is more cost-effective than that of D5 1/4NS.

Keywords: D10-CaGluconate, D5 1/4NS, Effectiveness, Direct medical costs, Incremental cost-effectiveness ratio.

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How to Cite
Ningsih, F., Sauriasari, R., & Saptaningsih, A. B. (2017). COST-EFFECTIVENESS ANALYSIS ON THE USE OF PARENTERAL NUTRITION WITH D10-CA GLUCONATE AND D5 1/4NS IN NORMAL-WEIGHT NEONATES WITH RESPIRATORY DISTRESS SYNDROME. International Journal of Applied Pharmaceutics, 9, 63-66. https://doi.org/10.22159/ijap.2017.v9s1.36_42
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