COST-EFFECTIVENESS ANALYSIS ON THE USE OF PARENTERAL NUTRITION WITH D10-CA GLUCONATE AND D5 1/4NS IN NORMAL-WEIGHT NEONATES WITH RESPIRATORY DISTRESS SYNDROME


Fitria Ningsih, Rani Sauriasari, Agusdini Banun Saptaningsih

Abstract


Objectives: This retrospective cohort study aimed to compare the cost-effectiveness of using D10-CaGluconate and D5 1/4NS preparations in normalweight
neonatal patients with Respiratory Distress Syndrome (RDS) in Kambang General Hospital, Jambi, Indonesia.
Methods: The research was conducted from September 2014 to June 2015. The study participants were divided into two groups; D10-CaGluconate
was administered to 40 patients and D5 1/4NS to 43 patients. Effectiveness was assessed based on the changes in the physical examination results,
average weight gain (28.48 and 23.49 g/day), blood glucose levels (26.73 and 26.42 mg/dL), respiratory rate (−12.35 breaths/minute and −7.77
breaths/minute), pulse frequency (−10.98 and −8.07 ±), and body temperature (0.013°C and 0.012°C) of the patients in the D10-CaGluconate and
D5 1/4NS groups, respectively.
Results: The average direct medical costs of using D10-CaGluconate and D5 1/4NS were 458,290 IDR and 408,347 IDR, respectively. The average costeffectiveness
ratio value of total direct medical costs for D10-CaGluconate preparation was 35,207,467 IDR while that for D5 1/4NS was 33,958,602
IDR. The direct medical cost of the incremental cost-effectiveness ratio mean value of the D5 1/4NS preparation that compared to the D10-CaGluconate
preparation was 10,017,210 IDR.
Conclusions: The parenteral nutrition preparation of D10-CaGluconate is more cost-effective than that of D5 1/4NS.


Keywords


D10-CaGluconate, D5 1/4NS, Effectiveness, Direct medical costs, Incremental cost-effectiveness ratio.

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About this article

Title

COST-EFFECTIVENESS ANALYSIS ON THE USE OF PARENTERAL NUTRITION WITH D10-CA GLUCONATE AND D5 1/4NS IN NORMAL-WEIGHT NEONATES WITH RESPIRATORY DISTRESS SYNDROME

Keywords

D10-CaGluconate, D5 1/4NS, Effectiveness, Direct medical costs, Incremental cost-effectiveness ratio.

DOI

10.22159/ijap.2017.v9s1.36_42

Date

30-10-2017

Additional Links

Manuscript Submission

Journal

International Journal of Applied Pharmaceutics
Vol. 9, Special Issue (Oct.), 2017 [PTMDS 2017] Page: 63-66

Online ISSN

0975-7058

Statistics

11 Views | 16 Downloads

Authors & Affiliations

Fitria Ningsih
1Department of Pharmacy, Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia.
Indonesia

Rani Sauriasari
2Department of Apothecary, Kambang General Hospital, Jambi, Indonesia.
Indonesia

Agusdini Banun Saptaningsih
Directorate General of Pharmaceutical Services and Medical Devices, Ministry of Health, Indonesia.
Indonesia


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