EFFECTIVENESS OF A MEDICATION BOOKLET AND COUNSELING ON TREATMENT ADHERENCE IN TYPE 2 DIABETES MELLITUS PATIENTS


Iin Presetiawati, Retnosari Andrajati, Rani Sauriasari

Abstract


Objective: This study aimed to evaluate the effectiveness of counseling and the use of a medication booklet on the level of treatment compliance
through reduced levels of glycated hemoglobin (HbA1C) and Morisky Medication Adherence Scale (MMAS-8) scores in patients with type 2 diabetes
mellitus.
Methods: This pre-experimental prospectively study was conducted at Dr. Adjidarmo General Hospital, KabupatenLebak, Banten Province, Indonesia.
The study sample consisted of 30 type 2 diabetic patients who met the inclusion and exclusion criteria and who underwent a counseling intervention
session and received a medication booklet. Compliance was measured against the MMAS-8 scores and HbA1C levels before the intervention and after
10 weeks of administration of counseling and receipt of the booklet).
Results: The MMAS-8 scores before and after the intervention were 2.63±1.50 and 0.7±1.18, respectively. The HbA1C levels before and after the
intervention were 11.31±2.95 and 8.12±2.79, respectively. The measurement results for MMAS-8 and HbA1C were analyzed using the Wilcoxon test.
Conclusions: The analysis showed a significant difference (p<0.001) between the HbA1Cvalues and MMAS-8 scores before and after the intervention.
Therefore, this study’s finding indicate that the provision of counseling and an informational booklet can improve type 2 diabetes mellitus patient
compliance with treatment.


Keywords


Morisky Medication Adherence Scale, Glycated hemoglobin, Compliance, Blood glucose, Type 2 diabetes mellitus, Counseling, Medication booklet.

| PDF |

References


International Diabetes Federation. Diabetes Atlas. 6th ed. Brussels:

IDF Executive Office; 2013. Available from: http://www.idf.org/

diabetesatlas.

PB PERKENI since the year meetingi. Konsensus Pengelolaan Dan

Pencegahan Diabetes Melitus Tipe 2 di Indonesia. Jakarta: Perkumpulan

Endokrinologi Indoesia; ; 2011.

Riset Kesehatan Dasar. Badan Penelitian dan Pengembangan Kesehatan.

Jakarta: Departemen Kesehatan, Republik Indonesia; 2007.

Riset Kesehatan Dasar. Badan Penelitian dan Pengembangan Kesehatan.

Jakarta: Departemen Kesehatan, Republik Indonesia; 2013.

World Health Organization. Adherence to Long-Term Therapies:

Evidence for Action. Geneva: World Health Organization; 2003.

Departemen Kesehatan RI. Pharmaceutical care untuk penyakit

diabetes mellitus. Jakarta: Direktorat Bina Farmasi Komunitas Dan

Klinik Direktorat Jenderal Bina Kefarmasian Dan Alat Kesehatan;

Adisa R, Fakeye TO, Fasanmade A. Medication adherence among

ambulatory patients with Type 2 diabetes in a tertiary healthcare setting

in southwestern Nigeria. Pharm Pract (Granada) 2011;9(2):72-81.

Siregar CJ, Kumolosasi E. Farmasi Klinik Teori dan Penerapan. Jakarta:

EGC; 2006.

Stratton M, Adler AI, Neil HA, Matthews DR, Manley SE, Cull CA,

et al. Association of glycaemia with macro vascular and micro

vascular complications of Type 2 diabetes (UKPDS 35): Prospective

observational study. Br Med J 2000;321(7258):405-12.

Morisky DE, DiMatteo MR. The morisky 8-item self-report measure

of mediacation-taking behavior (MMAS-8). J Clin Epidemiol

;64:262-3.

Notoatmodjo S. Metodologi Penelitian Kesehatan. Jakarta: Rineka

Cipta; 2011.

Mihardja L. Associated factors of blood glucose control in diabetes

mellitus patients in urban areas of Indonesia. Majalah Kedokt Indones

;59(9):418-24.

Trisnawati SK, Setyorogo S. Risk factors of type 2 diabetes mellitus

in primary health care center of Cengkareng West Jakarta in 2012. J

Ilmiah Kesehatan 2013;5(1):6-11.

Waspadji S. Diabetes Melitus, Penyulit Kronik dan Pencegahannya.

Jakarta: FKUI; 2013.

Lacy CF, Armstrong LL, Goldman MP, Lance LL. Drug Information

Handbook. 14th ed. North American: Lexi Comp; 2011.

Rubin RR. Adherence to pharmacologic therapy in patients with Type 2

diabetes mellitus. Am J Med 2005;118 Suppl 5A:27S-34.

Sukardji K. Penatalaksanaan Gizi Pada Diabetes Melitus. Jakarta:

FKUI; 2013.

Keban SA, Purnomo LF, Mustofa M. Evaluation of Pharmacist

education to type 2 diabetes mellitus patients in Dr. Sardjito Hospital

Yogyakarta. J Ilmu Kefarmasian Indones 2013;11:45-52.

Delamanter AM. Improving patient adherence. Clin Diabetes J

;24(2):771-7.

Wolfe RR. Metabolic interactions between glucose and fatty acids in

humans. Am J Clin Nutr 1998;67 3 Suppl:519S-26.

Indiyani P, Supriyatno H, Santoso A. The effect of aerobic physical

gymnastic training in reducing blood glucose level in type 2 diabetes

mellitus patients in primary health care center. Bukateja Purbalingga.

Media Ners 2007;1(2):89-99.

Willi C, Bodenmann P, Ghali WA, Faris PD, Cornuz J. Active smoking

and the risk of Type 2 diabetes: A systematic review and meta-analysis.

JAMA 2007;298:2654-64.

American Diabetes Association. Standards of medical care in

diabetes--2014. Diabetes Care 2014;37 Suppl 1:S14-80.

Int J App Pharm, Special Issue (October)

Presetiawati et al.

Chawla R, Thakur P, Chowdhry A, Jaiswal S, Sharma A, Goel R, et al.

Evidence based herbal drug standardization approach in coping with

challenges of holistic management of diabetes: A dreadful life style

disorder of 21st century. J Diabetes Metab Disord 2013;12(1):35.

Gupta PD, De A. Diabetes mellitus and its herbal treatment. Int J Res

Pharm Biomed Sci 2012;3(2):706-21.

Huseini HF, Kianbakht S, Hajiaghaee R, Dabaghian FH. Antihyperglycemic

and anti-hypercholesterolemic effects of Aloe vera leaf

gel in hyperlipidemic Type 2 diabetic patients: A randomized doubleblind

placebo-controlled clinical trial. Planta Med 2012;78(4):311-6.

Ngo MQ, Nguyen NN, Shah SA. Oral Aloe vera for treatment

of diabetes mellitus and dyslipidemia. Am J Health Syst Pharm

;67(21):1804-11.

Al-Qazaz HK, Hassali MA, Shafie AA, Sulaiman SA, Sundram S,

Morisky DE. Use of 8-item morisky medication adherence scale for the

assesment of medication adherence in Type 2 diabetes mellitus. Value

Health 2010;13(7):A528.

Hartono B. Promosi Kesehatan di Puskesmas dan Rumah Sakit. Jakarta:

Rineka Cipta; 2010.

Suppapitiporn S, Chindavijak B, Onsanit S. Effect of diabetes

drugc ounseling by pharmacist, diabetic disease booklet and special

medication containers on glycemic control of Type 2 diabetes mellitus:

A randomized controlled trial. J Med Assoc Thai 2005;88(4):S134-41.

Lindenmeyer A, Hearnshaw H, Vermeire E, Van Royen P, Wens J,

Biot Y. Interventions to improve adherence to medication in people

with Type 2 diabetes mellitus: A review of the literature on the role of

pharmacists. J Clin Pharm Ther 2006;31(5):409-19.

Dahlan S. Statistik Untuk Kedokteran dan Kesehatan. 5th ed. Jakarta:

Salemba Medika; 2011.

Krousel-Wood M, Islam T, Webber LS, Re RN, Morisky DE, Muntner P.

New medication adherence scale versus pharmacy fill rates in seniors

with hypertension. Am J Manag Care 2009;15(1):59-66.

Sarwono J. Metode Penelitian Kuantitatif dan Kualitatif. Yogyakarta:

Graha Ilmu; 2006.




About this article

Title

EFFECTIVENESS OF A MEDICATION BOOKLET AND COUNSELING ON TREATMENT ADHERENCE IN TYPE 2 DIABETES MELLITUS PATIENTS

Keywords

Morisky Medication Adherence Scale, Glycated hemoglobin, Compliance, Blood glucose, Type 2 diabetes mellitus, Counseling, Medication booklet.

DOI

10.22159/ijap.2017.v9s1.24_29

Date

30-10-2017

Additional Links

Manuscript Submission

Journal

International Journal of Applied Pharmaceutics
Vol. 9, Special Issue (Oct.), 2017 [PTMDS 2017] Page: 28-31

Online ISSN

0975-7058

Statistics

10 Views | 18 Downloads

Authors & Affiliations

Iin Presetiawati
Department of Pharmaceutics, Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia.
Indonesia

Retnosari Andrajati
Department of Pharmaceutics, Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia.
Indonesia

Rani Sauriasari
Department of Pharmaceutics, Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia.
Indonesia


Refbacks

  • There are currently no refbacks.