SYNTHESIS OF COPPER AND MANGANESE COMPLEXES WITH METHIONINE AND TRYPTOPHAN: ANALYSIS BY ATOMIC ABSORPTION SPECTROPHOTOMETRY

  • Azkaafina Hindersah Department of Pharmacy, Faculty of Pharmacy, Universitas Indonesia, Depok, 16424, Indonesia.
  • Harmita . Department of Pharmacy, Faculty of Pharmacy, Universitas Indonesia, Depok, 16424, Indonesia.
  • Catur Jatmika Department of Pharmacy, Faculty of Pharmacy, Universitas Indonesia, Depok, 16424, Indonesia.

Abstract

Objective: In this study, we aimed to create complexes consisting of copper and manganese mineral elements and amino acids.
Methods: We determined the mineral element levels both bound and in their free state using atomic absorption spectrophotometry. The synthesized
complexes were characterized using infrared spectrophotometry, while the free and bound mineral contents were separated using ion exchange
chromatography.
Results: Our results demonstrated that the synthesis of such complexes was successful. The free mineral contents of the copper-methionine, coppertryptophan,
and manganese-methionine complexes were 4.52, 6.53, and 0.056 mg/kg, respectively, while the bound mineral contents of the coppermethionine,
copper-tryptophan, manganese-methionine, and manganese-tryptophan complexes were 96.885, 114.974, 57.778, and 49.624 mg/kg,
respectively.
Conclusion: The synthesis of copper and manganese complexes were successfully formed and analysis.
Keywords:

Keywords: Atomic absorption spectrophotometry, Copper, Infrared, Ion exchange chromatography column, Manganese, Methionine, Tryptophan.

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How to Cite
Hindersah, A., ., H., & Jatmika, C. (2018). SYNTHESIS OF COPPER AND MANGANESE COMPLEXES WITH METHIONINE AND TRYPTOPHAN: ANALYSIS BY ATOMIC ABSORPTION SPECTROPHOTOMETRY. International Journal of Applied Pharmaceutics, 10(1), 110-115. https://doi.org/10.22159/ijap.2018.v10s1.23
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