ANALYSIS OF TUBERCULOSIS TREATMENT SUITABILITY AND THE DRUG SUPERVISOR’S ROLE IN A COMMUNITY HEALTH CENTER IN PADEMANGAN SUBDISTRICT, NORTH JAKARTA

  • CITRA FEBRIONY Department of Pharmacology and Therapeutics, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
  • PURWANTYASTUTI . Department of Pharmacology and Therapeutics, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
  • MEANALDI RASMIN Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
  • VIVIAN SOETIKNO Department of Pharmacology and Therapeutics, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.

Abstract

Objective: Appropriate tuberculosis (TB) treatment guidelines are one of the many factors that influence the success of TB treatment. The patient’s
drug supervisor is a functional role that is part of the directly observed treatment short course, a program to support the success of TB treatment.
The aim of this study was to analyze the TB treatment suitability in a community health center and the benefit of treatment compliance supervision
by the patient’s designated drug supervisor.
Methods: We conducted a cross-sectional study in the Community Health Center of Pademangan subdistrict, North Jakarta, involving 205 subjects to
analyze appropriate fixed-dose combination (FDC) anti-TB drug administration and an experimental study involving 23 control group TB patients and
23 intervention group TB patients to assess the benefit of supervision by each patient’s drug supervisor.
Results: The association of FDC anti-TB drug side effects with the success of TB treatment was not statistically significant (p=0.173). There was
an increase in drug supervisor knowledge of 8.6% in the intervention group and 13% in the control group. There was no statistically significant
association between the knowledge of the drug supervisor and the 2nd month (p=0.575) and the 6th month of sputum treatment.
Conclusion: Minor side effects of FDC anti-TB drug did not affect the success of TB treatment; therefore, treatment was continued if these adverse
events occurred. There were no correlations between the drug supervisor knowledge level with medication compliance or with sputum conversion
(months 2 and 6).

Keywords: Fixed-dose combination, Drug supervisor, Tuberculosis

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FEBRIONY, C., ., P., RASMIN, M., & SOETIKNO, V. (2019). ANALYSIS OF TUBERCULOSIS TREATMENT SUITABILITY AND THE DRUG SUPERVISOR’S ROLE IN A COMMUNITY HEALTH CENTER IN PADEMANGAN SUBDISTRICT, NORTH JAKARTA. International Journal of Applied Pharmaceutics, 11(1), 272-276. https://doi.org/10.22159/ijap.2019.v11s1.030
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Original Article(s)