BACOPA MONNIERI

PHARMACOGNOSTIC AND PHARMACOLOGICAL ASPECT OF BACOPA MONNIERI - A REVIEW


Pushpendra Kumar Jain, Debajyoti Das, Puneet Jain, Prachi Jain, Pushpendra Kumar Jain

Abstract


It is said that the use of Bacopa monnieri for memory enhancement goes back 3000 years or more in India, when it was cited for its medicinal properties, especially the memory enhancing capacity, in the Vedic texts "Athar-Ved Samhila" (3:1) of 800 B.C. and in Ayurveda. In the folklore of Indian medicine, several herbs have been used traditionally as brain or nerve tonics. One of the most popular of these neurotonics is Bacopa monnieri, a well known memory booster. Brahmi has been administered at religious institutions to help students to enhance their memory for learning ancient, religious hymns.

It is also used as cardio-tonic, tranquilizer and sedative, improves process of learning, Restores memory, enhances power of speech and imagination, diuretic and nervine tonic, anti stress, for nervous and mental strain, use in insanity, epilepsy, hysteria, aesthenia, nervous breakdown. It is a small, creeping succulent herb. The leaf and flower bearing stems are 10- 30 cm long and arise from creeping stems that form roots at the nodes with pale blue or pinkish white flowers belonging to  Family  Scrophulariaceae grown nearly banks of freshwater streams and ponds, paddy fields and other damp places. The chief Phyto-constituents present are brahmine, herpestine, alkaloids and saponins.

 

Keywords: Ayurveda, Brahmi, memory booster, herb, neurotonics, tranquilizer.

 


| PDF |

References


The Ayurvedic Pharmacopoeia of India. Part 1, vol. II. 1* edn. New Delhi: Government of India; Ministry of Health and Family Welfare, Department of Indian Systems of Medicine and Homoeopathy; 1999; p. 25-26,

Indian Herbal Pharmacopoeia. Vol. I. Mumbai: Indian Drug Manufacturers' Association and Jammu Tawi: Regional Research Laboratory (CS1R); 1998; p. 30-32.

Datta SC, Mukerji B. Pharmacognosy of Indian Leaf Drugs. Pharmacognosy Laboratories, Bull No. 2. Calcutta; Ministry of Health, Government of India; 1952; p. 62,

Aiyer KN, Kolammal M. Pharmacognosy of Ayurvedic Drugs. Scries 1, No. 8. Trivandrum: Department of Pharmacognosy, University of Kerala; 1964; p. 27-29.

Singh J. Studies on distinguishing characters of plant species used as ‘brahmi’. Nagarjun 1988; 23: 153-156.

Abhang.R. 1993. Study „to evaluate the. effect of a micro(Suksma) derived from Brahmi (Herpestis monnierra) on students of average intelligence: J Res Ayur Siddlha 14. 10-24.

Charaka, Charaka samhita, Chikitsa sthana, Varanasi; Choukamba Sanskrit series, 2002, P. 385.

VV Sivaranjan and Indira Balachandran, Ayurvedic drugs and their plant sources, New Delhi; Published by Oxford & IBH Publishing Co. Pvt. Ltd, 1994, P. 289.

P K Warrier, V P K Nambiar & C. Ramankutty Indian Medicinal Plants, Volume 1, Published Orient Longman Private Ltd, 1994, p.235.

Khare CP, Indian Medicinal Plants an Illustrated Dictionary, New Delhi, Springer; 2007, p.77.

Nadakarni AK. Dr. KM Nadakarni’s, Indian Materia Medica, Popular Prakashan, Bomaby, 1976. p579.

Gamble JS. Flora of the presidency of Madras. Botanical survey of India, Calcutta, 1925. Vol.II, p.556.

Wallis TE. Textbook of Pharmacognosy. Delhi; CBS Publishers and Distributors; 1985, p572.

Evans WC. Trease and Evans Pharmacognosy, London: Bailliere Tindall; 1989, p530.

O’Brien TP, Feder N, Mc Cull ME. Polychromatic staining of plant cell walls by toluidine blue-O. Protoplasma 1964; 59: 364-373.

Quality Control Methods for Medicinal Plant Materials, WHO, Geneva, 1998, p.16- 27.

Shanmugasundaram ER Akbar GK, Shanmugasundaram B,Rahmighritham KR. An Ayurvedic herbal formula for the control of epilepsy. J Ethnopharmacol 1991;33:269-76.

Pushpendra Kumar Jain, Debajyoti Das, Puneet Jain. Evaluating Hair Growth Activity of Herbal Hair Oil. International Journal of PharmTech Research 2016; 9(3):321-327.

Singh HK, Shanker G, Patnaik GK. Neuropharmacological Pharmacol 1996;28:47.

Bhattacharya SK, Ghosal S. Anxiolytic activity of a standardized extract of Bacopa monniera: an experimental study. Phytomed 1998;5:77-82.

Tripathi YB, Chaurasia S, Tripathi E, Upadhyay A, Dubey GP.Bacopa monniera Linn. as an antioxidant: mechanism of action. Ind J Exp Biol 1996;34:523-6.

Govindarajan R, Vijayakumar M, Pushpangadan P. Antioxidant approach to disease management and the role of ‘Rasayana’ herbs. Ayur J Ethnopharmacol 2005;99:165-78.

Chowdhuri DK, Parmar D, Kakkar P, Shukla R, Seth PK, Srimal RC. Antistress effects of bacosides of Bacopa monnieri: modulation of Hsp70 expression, superoxide dismutase and cytochrome P450 activity in rat brain. Phytother Res 2002;16:639-45.

Bhakuni DS, Dhar ML, Dhar MM, Dhawan BN, Mehrotra BN.Screening of Indian plants for biological activity: Part II. Ind J Exp Biol 1969;7:250-62.

Rao CH, Sairam K, Goel RK. Experimental evaluation of Bacopa monniera on rat gastric ulceration and secretion. Ind J Physiol Pharmacol 2000;44:435-41.

Dharmani P, Palit G. Exploring Indian medicinal plants for antiulcer activity. Ind J Pharmacol 2006;38:95-9.

Goel RK, Sairam K. Anti ulcer drugs from indigenous sources with emphasis on Musa sapientum, tamrabhasma, Asparagus racemosus and zinzibar officinale. Ind J Pharmacol 2002;34:100-10.

Sairam K, Rao CV, Babu MD, Goel RK. Prophylactic and curative effects of Bacopa monniera in gastric ulcer models. Phytomed 2001;8:423-30.

Sumathy T, Govindasamy S, Balakrishna K, Veluchamy G.Protective role of Bacopa monniera on morphine-induced brain mitochondrial enzyme activity in rats. Fitoterapia 2002;73:381-5.

Kar A, Panda S, Bharti S. Relative efficacy of three medicinal plant extracts in the alteration of thyroid hormone concentrations in male mice. JEth nopharmacol 2002;81:281-285.

Singh RH, Singh L. Studies on the anti-anxiety effect of the Medyha Rasayana drug, Brahmi (Bacopa monnieraWettst.) – Part 1. J Res Ayur Siddha 1980;1:133-148.

Shader RI, Greenblatt DJ. Pharmacotherapy of acute anxiety.In: Bloom FE, Kupfer DJ. editors. Psycopharmacology: Fourth generation of progress. New York: Raven Press; 1995. p. 1341-8.

Dar A, Channa S. Calcium antagonistic activity of Bacopa monniera on vascular and intestinal smooth muscles of rabbit and guinea pig. J Ethnopharmacol 1999; 66:167-74.

Yadav SK, Jain AK, Tripathi SN, Gupta JP. Irritable bowel syndrome: therapeutic evaluation of indigenous drugs. Indian J Med Res 1989; 90:496- 503.

Jain, Pushpendra Kumar. "ALTERNATIVE HERBAL DRUGS USED FOR TREATING HAIR DISEASE." Asian Journal of Pharmaceutical and Clinical Research 2016; 9(1):75-77.

Jain, Pushpendra Kumar, and Dass Dj. "EVALUATING HAIR GROWTH POTENTIAL OF SOME TRADITIONAL HERBS." Asian Journal of Pharmaceutical and Clinical Research 2015; 8(6):150-152.

Bhoomi B. Joshi., et al., “ In Vitro Phytochemical Analysis And Anti-Microbial Activity Of Crude Extract Of Bacopamonniera” Bulletin Of Pharmaceutical And Medical Sciences (Bopams),Vol:1 Issue :2 ,2013.

Jain, P. K., Himanshu Joshi, and D. J. Dass. "Drug that Causes Hair Loss and Promotes Hair Growth-A Review." Int J Res Pharm Biomed Sciences 3.4 (2012): 1476-82.




About this article

Title

PHARMACOGNOSTIC AND PHARMACOLOGICAL ASPECT OF BACOPA MONNIERI - A REVIEW

Date

01-06-2016

Additional Links

Manuscript Submission

Journal

Innovare Journal of Ayurvedic Sciences
Vol 4 Issue 3 2016 (June-July) Page: 7-11

Online ISSN

2321-6824

Statistics

98 Views | 325 Downloads

Authors & Affiliations

Pushpendra Kumar Jain
Department of Pharmacy, Naraina Group of Institutions, Panki-Kanpur, Uttar Pradesh
India

Debajyoti Das
Department of Pharmacy, School of Pharmaceutical Sciences, Siksha ‘O’ Anusandhan University, Bhubaneswar, Odisha
India

Puneet Jain
Maharana Pratap Education Center, Kalyanpur, Kanpur, Uttar Pradesh
India

Prachi Jain
Dr. VSEC Panki-Kanpur, Uttar Pradesh
India

Pushpendra Kumar Jain
Department of Pharmacy, Naraina Group of Institutions, Panki-Kanpur, Uttar Pradesh
India


Article Tools



Refbacks