• Emmanuel O. Olorunsola Department of Pharmaceutics and Pharmaceutical Technology, University of Uyo, Uyo, Nigeria
  • Stephen O. Majekodunmi Department of Pharmaceutics and Pharmaceutical Technology, University of Uyo, Uyo, Nigeria




Afzelia gum, Liquid paraffin, Emulsifying properties, Density, Viscosity, Creaming


Objective: Afzelia africana gum has been shown to possess surface activity. It is a good alternative to sodium carboxy methylcellulose in terms of suspending properties. This work was aimed at evaluating the emulsifying properties of the gum in liquid paraffin emulsion.

Methods: Liquid paraffin emulsions (200 ml each) were prepared with different concentrations (1, 2, 3, 5 and 10 % w/v) of afzelia gum as an emulsifying agent. Similar preparations containing standard acacia gum at corresponding concentrations were also made. Liquid paraffin emulsions (200 ml each) were equally prepared using 60 ml liquid paraffin as the oily phase and 6 g of various combinations of afzelia gum and tween 80 as emulsifier blends. The emulsifier blends were of ratio 1:5, 1:2, 1:1, 2:1 and 5:1. The preparations were assessed for density and viscosity; and then for stability after 5 d of storage.

Results: The viscosity of emulsion containing 10 % w/v afzelia gum was 668.90 mPa.s while that of an emulsion containing the same concentration of acacia gum was 23.56 mPa. s. Emulsion containing 3 % w/v afzelia gum (having a creaming index of 16 %) was found to be more stable compared to the emulsion containing 10 % w/v acacia gum (having creaming index of 28 %). The viscosity and stability of emulsions containing emulsifier blends of afzelia gum and tween 80 increased with increase in the proportion of afzelia gum.

Conclusion: The gum is suitable for use at a concentration of 3 % w/v as an emulsifier in 30 % v/v liquid paraffin emulsion, and it is about three times better than acacia gum as an emulsifier. It is a good alternative to standard acacia gum for emulsification.



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Mahmud HS, Oyi AR, Allagh TS. Evaluation of the suspending properties of Khaya senegalensis gum in paracetamol suspension. Niger J Pharm Sci 2009;8:128-34.

Billany MR. Suspensions and emulsions. In: Aulton ME. editor. The design and manufacture of medicine. 3rd ed. Philadelphia: Churchill Livingstone, Elsevier; 2007. p. 383-405.

Chaudhari SP, Akuskar G, Salvankar SS, Bangar J. Evaluation of suspending and emulsifying properties of Citrullus lanatus seeds gum. Asian J Pharm Clin Res 2014;7:181-5.

Builders PF, Chukwu C, Obidike I, Builders MI, Attama AA, Adikwu MU. A novel xyloglucan gum from the seed of Afzelia africana se pers. Some functional and physiochemical properties. Int J Green Pharm 2009;3:112-8.

Olorunsola EO, Bhatia PG, Tytler BA, Adikwu MU. Physicosurface properties of afzelia and prosopis hemicellulosic gums: potential surface active agents. IOSR J Pharm Biol Sci 2015;10(4, Suppl 3):1-7.

Okorie O, Ibezim CNE, Nwachukwu N. Evaluation of suspending properties of a natural hydrocolloid from Afzelia africana. J Pharm Res 2011;10:112-5.

Asantewa Y, Ofori-Kwakye K, Kipo SL, Efsiapa-Boamah V, Johnson R. Investigation of emulsifying and suspending potential of cashew tree gum in pharmaceutical formulations. Int J Pharm Pharm Sci 2011;3:215-9.

Momoh MA, Adikwu MU. Determination of hydrophile-lipophile balance (HLB) of Bovine mucin for possible emulsifying properties. Animal Res Int 2008;5:840-2.

Lachman L, Liberman HA. The theory and practice of industrial pharmacy. Special Indian edition. New Delhi: CBS Publisher and Distributors; 2009. p. 479-94, 502-31.

Reilly Jr WJ. Pharmaceutical excipients. In: Felton LA. editor. Remington–Essentials of Pharmaceutics. London, United Kingdom: Pharmaceutical Press; 2013. p. 683-704.

Ibezim EC, Khanna M, Singh S, Uzuebenam CE. Afzelia africana seed gum: potential binder for tablet formulations. J Phytomed Ther 2006;11:38-48.

Nwokocha LM, Williams PA. Evaluating the potential of Nigeria plants as a source of industrial hydrocolloids. In: Williams PA, Philips GO. editors. Gums and stabilizers for the food industry 16. Great Britain: Royal Society of Chemistry Publishing; 2012. p. 27-44.

Golkar A, Nasirpour A, Keramat J, Desobry S. Emulsifying properties of Angum gum (Amygdalus scoparia Spach) conjugated ï‚¢-Lactoglobulin through Maillard type reaction. Int J Food Properties 2015;18:2042-55.

Attwood D. Disperse systems. In: Aulton ME. editor. The Design and Manufacture of Medicine. 3rd ed. Philadelphia: Churchill Livingstone, Elsevier; 2007. p. 70–98.



How to Cite

Olorunsola, E. O., and S. O. Majekodunmi. “EMULSIFYING PROPERTIES OF AFZELIA GUM IN LIQUID PARAFFIN EMULSION”. International Journal of Pharmacy and Pharmaceutical Sciences, vol. 8, no. 11, Nov. 2016, pp. 195-8, doi:10.22159/ijpps.2016v8i11.14509.



Original Article(s)