A CASE SERIES ON ANTI NMDAR ENCEPHALITIS


Reshma Reji, Sherin Alexander, Meenu Vijayan

Abstract


N-methyl-D-aspartate receptor (NMDAR) encephalitis is an autoimmune neurological disorder arising from the generation of antibodies which binds to the synaptic proteins. Here we present a case series of 3 cases where the different aspects of treating NMDAR encephalitis are dealt with. The association of ovarian teratoma and the importance of its removal before treating the encephalitis have been discussed in the second case. Apart from the first line and second line agents used in the therapy of NMDAR encephalitis, the importance of managing infections especially urinary tract infection and lower respiratory tract infection with antibiotics have also been discussed. The article also aims to throw light into the treatment of extrapyramidal side effects induced by antipsychotics. At the end, the significance of putting the patient on a ketogenic diet to manage refractory seizures associated with anti-NMDA receptor encephalitis has also been discussed based on reviewing literature.


Keywords


NMDAR Encephalitis, Synaptic proteins, Ovarian teratoma, Extrapyramidal side effects, Ketogenic diet

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References


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About this article

Title

A CASE SERIES ON ANTI NMDAR ENCEPHALITIS

Keywords

NMDAR Encephalitis, Synaptic proteins, Ovarian teratoma, Extrapyramidal side effects, Ketogenic diet

DOI

10.22159/ijpps.2017v9i4.15264

Date

27-02-2017

Additional Links

Manuscript Submission

Journal

International Journal of Pharmacy and Pharmaceutical Sciences
Vol 9, Issue 4, 2017 Page: 220-222

Online ISSN

0975-1491

Statistics

69 Views | 23 Downloads

Authors & Affiliations

Reshma Reji
Department of Pharmacy Practice, Amrita School Of Pharmacy, Amrita viswavidyapeetham, Amrita university, Kochi, Kerala, India
India

Sherin Alexander
Department of Pharmacy Practice, Amrita School of Pharmacy, Amrita Viswa Vidyapeetham, Amrita University, Kochi, Kerala, India

Meenu Vijayan
Department of Pharmacy Practice, Amrita School of Pharmacy, Amrita Viswa Vidyapeetham, Amrita University, Kochi, Kerala, India


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