HERBAL MEDICINES AS NEUROPROTECTIVE AGENT: A MECHANISTIC APPROACH


Supriya Roy, Himani Awasthi

Abstract


Neurodegeneration refers to a condition of neuronal death occurring as a result of progressive disease of long termand is becoming a major health problem in the 21st century. Neurons degenerated are not replaced resulting in cognitive loss ,many neurodegenerative disorders, such as schizophrenia, depression, Alzheimer's Disease (AD) dementia, cerebrovascular impairment, seizure disorders, head injury, Parkinsonism. Neuroprotection refers to the strategies and possible mechanisms that are able to protect the central nervous system (CNS) against neuronal injury and neurodegenerative disorders. The past decade has witnessed an intense interest in herbal plants having long-term health promoting or medicinal qualities. Comprehensive research and discovery has demonstrated that natural products, medicinal herbs, plant extracts, and their metabolites, have great potential as neuroprotective agent. Although the precise mechanisms of action of herbal drugs have yet to be determined, some of them have been shown to exert anti-inflammatory and/or antioxidant effects. Thus the herbal plants can be a valuable source of drug against neurodegenerative disorders which will require high-throughput screening. This review will highlight the role of herbal plants and their phytoconstituents against neurodegenerative diseases and other related disorders, focusing on their mechanism of action and therapeutic potential.

 

Keywords:


Keywords


Alzheimer’s disease, Antioxidant, Dementia, Herbal medicine, Neurodegenerative diseases, Neuroprotective plant.

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About this article

Title

HERBAL MEDICINES AS NEUROPROTECTIVE AGENT: A MECHANISTIC APPROACH

Keywords

Alzheimer’s disease, Antioxidant, Dementia, Herbal medicine, Neurodegenerative diseases, Neuroprotective plant.

DOI

10.22159/ijpps.2017v9i11.19444

Date

01-11-2017

Additional Links

Manuscript Submission

Journal

International Journal of Pharmacy and Pharmaceutical Sciences
Vol 9, Issue 11, 2017 Page: 1-7

Online ISSN

0975-1491

Statistics

123 Views | 15 Downloads

Authors & Affiliations

Supriya Roy
Amity Institute of Pharmacy, Amity University, Lucknow Campus, Uttar Pardesh 226028, India
India

Himani Awasthi
Amity Institute of Pharmacy Amity University Uttar Pradesh Lucknow
India


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