PRETREATMENT VARIATIONS IN HAEMATOLOGICAL PARAMETERS OF BREAST CANCER PATIENTS


Abdullatif Abdulaziz Al-arifi, Ashok Kumar, Sridevi Chigurupati, Muhammad Jawed, Thunga Pandurangan

Abstract


Objective: The objective of the presented study was to analyze the haematological parameters in female breast cancer (BC) patients before the start of the treatment.

Methods: The study was conducted among female BC patients, visited King Fahd Hospital (KFH), Al Ahsa, Kingdom of Saudi Arabia (KSA) from January 2013 to December 2016. A retrospective analytical study was conducted. We analyzed the relationship of haematological parameters with various stages of breast cancer before the start of any treatment. We used complete blood count (CBC) reports to analyze the haematological parameters. The mean age of the patients was 57 y (31-83 y). Most of the patients were postmenopausal (51-59 y old). We divided the patients into 4 groups according to the disease stage, i.e., stage 1 (S1) to stage 4 (S4).

Results: Among altered blood parameters, decreased haemoglobin (Hb 4.5-11 g/dl) and increased erythrocyte sedimentation rate (ESR 37–49 mm/first hour) in S1 to S4, increased neutrophil count in S3 and S4 (8.3-9.6 x103/mm3), and increased lymphocyte count (4-7.2 x103/mm3) in S1 and S2 patients were found.

Conclusion: We found significant variations in haematological parameters at different stages of breast cancer. CBC is indeed an efficient and cost-effective investigation. By managing these parameters, treatment efficacy and survival rate of BC patients may be augmented.


Keywords


Breast cancer, Haemoglobin, Erythrocyte sedimentation rate, Neutrophilia, Lymphocytosis

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About this article

Title

PRETREATMENT VARIATIONS IN HAEMATOLOGICAL PARAMETERS OF BREAST CANCER PATIENTS

Keywords

Breast cancer, Haemoglobin, Erythrocyte sedimentation rate, Neutrophilia, Lymphocytosis

DOI

10.22159/ijpps.2018v10i2.23669

Date

01-02-2018

Additional Links

Manuscript Submission

Journal

International Journal of Pharmacy and Pharmaceutical Sciences
Vol 10, Issue 2, 2018 Page: 157-161

Online ISSN

0975-1491

Statistics

58 Views | 24 Downloads

Authors & Affiliations

Abdullatif Abdulaziz Al-arifi
College of Medicine, King Faisal University, Al Ahsa, Kingdom of Saudi Arabia
Saudi Arabia

Ashok Kumar
Department of Pathology, Faculty of Medicine, AIMST University, Semeling, Kedah, Malaysia
Malaysia

Sridevi Chigurupati
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, AIMST University, Semeling, Kedah, Malaysia
Malaysia

Muhammad Jawed
Sindh Institute of Ophthalmology and Visual Science, Hyderabad
Pakistan

Thunga Pandurangan
Department of Surgery, Faculty of Medicine, AIMST University, Semeling, Kedah, Malaysia
Malaysia


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