• DEEPENDRA THAKUR Department of Microbiology, Banglore University, Banglore, India,
  • KAMANA SAHANI Department of Microbiology, Andhra University, Visakhapatnam, India


Objective: The objective of the present investigation was to find antimicrobial and MIC of endophytic fungi Fusarium sp. isolated from Tephrosia purpurea root.

Methods: Well diffusion assay was performed to find out the antimicrobial activity and Resazurin dye reduction method was performed to find out MIC of the extract.

Result: The extract showed the highest zone of inhibition of 22.66±0.57 mm, (Bacillus subtilis, MTCC-441) for Gram-positive bacteria and 20.66±0.57 mm, (E. coli, MTCC-443) for Gram-negative bacteria. Furthermore, the MIC of the extract was found to be (31.25 µg/ml-125 µg/ml).

Conclusion: Hence, the endophytic fungi isolated from the Tephrosia purpurea root, i.e. Fusarium sp. showed good antimicrobial activity and hence can be used to find a novel drug.

Keywords: Endophytes, Antimicrobial, MIC, Tephrosia purpurea root, Fusarium sp


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How to Cite
THAKUR, D., and K. SAHANI. “IN VITRO ANTIMICROBIAL ACTIVITY AND MIC OF THE EXTRACELLULAR ETHYL ACETATE CRUDE EXTRACT OF ENDOPHYTIC FUNGI FUSARIUM SP. ISOLATED FROM TEPHROSIA PURPUREA ROOT”. International Journal of Pharmacy and Pharmaceutical Sciences, Vol. 11, no. 3, Jan. 2019, pp. 48-53, doi:10.22159/ijpps.2019v11i3.28230.
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