• SHIKHA SANORIA Department of Pharmacology, CT Institute of Pharmaceutical Sciences, Jalandhar
  • ZULFKAR LATIEF QADRIE Department of Pharmacology, CT Institute of Pharmaceutical Sciences, Jalandhar
  • SURYA PRAKASH GAUTAM Department of Pharmaceutics, CT Institute of Pharmaceutical Sciences, Jalandhar
  • AMIT BARWAL Department of Pharmacology, CT Institute of Pharmaceutical Sciences, Jalandhar



Hepatoprotective, Wound healing, Antioxidant, Laxative, Anti-inflammatory


Cassia fistula Linn. is also called a “golden shower”. It is aboriginal to India, Sri Lanka and diffused in various countries, including Mexico, China, Mauritius, East Africa, South Africa, and West Indies. Plant and its parts, such as bark, fruit, leaves, and seeds, are used traditionally to cure diseases. Traditionally the plant possesses hepatoprotective, antipyretic, anti-inflammatory, leukotriene inhibition, antitussive activity, antioxidant, wound healing, hypo-lipidemia, anticancer, antidiabetic, central nervous system activity, antiulcer, antibacterial, antifertility, larvicidal and ovicidal, antifeedant, laxative, anti-epileptic, antimicrobial, urease inhibition, antifungal, anti-tobacco mosaic virus activities. The review contains botanical information, constituents and pharmacological leverages of the plant. The review draws attention towards the traditional, phytochemical and pharmacological knowledge accessible on Cassia fistula Linn, which would be beneficial for research scholars to develop novel chemical entities. This review article is written after studying most of the journal’s articles, which were published between 1998 to 2019.


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Rajeswari R, Thejomoorthy P, Mathuram LN, Raju KV. Anti-inflammatory activity of Cassia fistula linn. bark extracts in sub-acute models of inflammation in rats. Tamil Nadu J Vet Anim Sci 2006;2:193-9.

Nirmala J Eliza, M Rajalakshmi, P Edel, P Daisy. Effect of hexane extract of Cassia fistula barks on blood glucose and lipid profile in streptozotocin-diabetic rats. Int J Pharmacol 2008;4:292-6.

Senthil Kumar M, Sripriya R, Vijaya Raghavan H, Sehgal PK. Wound healing potential of Cassia fistula on an infected albino rat model. J Surg Res 2006;131:283-9.

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UC Gupta, GC Jain. Study on the hypolipidemic activity of cassia fistula. Legume Rats Asian J Exp Sci 2009;23:241-8.

Gupta M, Mazumder U, Rath N, Mukhopadhyay D. Antitumor activity of methanolic extract of Cassia fistula L. seed against ehrlich ascites carcinoma. J Ethnopharmacol 2000;72:151-6.

Remya RR, Rajasree SRR, Aranganathan L, Suman TY. An investigation on the cytotoxic effect of bioactive AgNPs synthesized using Cassia fistula flower extract on breast cancer cell MCF-7. Biotechnol Rep 2015;8:110–5.

Duraipandiyan V, Baskar AA, Ignacimuthu S, Muthukumar C, Al-Harbi NA. Anticancer activity of rhein isolated from Cassia fistula L. flower. Asian Pac J Trop Dis 2012;2:517-23.

Kanika Verma, Shanthi Veerappapillai, Ramanathan Karuppasamy. Exploration of plant bioactive from cassia fistula leaves for the treatment of ovarian cancer: an integrative approach. Asian J Pharm Clin Res 2016;9:182-8.

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Daisy P, Saipriya K. Biochemical analysis of Cassia fistula aqueous extract and phytochemically synthesized gold nanoparticles as hypoglycemic treatment for diabetes mellitus. Int J Nanomed 2012;7:1189-202.

Agnihotri A, Singh V. Effect of Tamarindus indica Linn. and Cassia fistula Linn. stem bark extracts on oxidative stress and diabetic conditions. Acta Pol Pharm 2013;70:1011-9.

Pitchai D, Manikkam R. Hypoglycemic and insulin-mimetic impact of catechin isolated from Cassia fistula: a substantiate in silico approach through docking analysis. Med Chem Res 2012;21:2238–50.

Sartorelli P, Andrade SP, Melhem MS, Prado FO, Tempone AG. Isolation of antileishmanial sterol from the fruits of Cassia fistula using bio guided fractionation. Phytother Res 2007;21:644-7.

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M Govindarajan, A Jebanesan, T Pushpanathan. Larvicidal and ovicidal activity of Cassia fistula linn. leaf extract against filarial and malarial vector mosquitoes. Parasitol Res 2008;102:289-92.

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Mehmood S, Lateef M, Omer MO, Anjum AA, Rashid MI, Shehzad W. Adulticidal and larvicidal activity of Cassia fistula and Piper nigrum against malaria vector. Sci Int (Lahore) 2014;26:331-4.

Sakulpanich A, Chewchinda S, Sithisarn P, Gritsanapan W. Standardization and toxicity evaluation of Cassia fistula pod pulp extract for an alternative source of the herbal laxative drug. Phcog J 2012;4:6-12.

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Sony P, Kalyani M, Jeyakumari D, Kannan I, Sukumar RG. In vitro antifungal activity of Cassia fistula extracts against fluconazole-resistant strains of Candida species from HIV patients. J Mycol Med 2018;28:193-200.

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Rashid MI, Mujawar LH, Mujallid MI, Shahid M, Rehan ZA, Khan MKI, et al. Potent bactericidal activity of silver nanoparticles synthesized from Cassia fistula fruit. Microb Pathog 2017;107:354-60.

Arulpandi, R Sangeetha. Antibacterial activity of fistulin: a protease inhibitor purified from the leaves of Cassia fistula. Int Sch Res Notices 2012:1-4. 2012/584073.

Seyyednejad SM, Motamedi H, Vafei M, Bakhtiari A. The antibacterial activity of Cassia fistula organic extracts. Jundishapur J Microbiol 2014;7:e8921.

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Duraipandiyan V, Ignacimuthu S. Antibacterial and antifungal activity of Cassia fistula L.: an ethnomedicinal plant. J Ethnopharmacol 2007;112:590-4.

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Lachumy SJ, Zuraini Z, Sasidharan S. Antimicrobial activity and toxicity of methanol extract of Cassia fistula seeds. Res J Pharm Biol Chem Sci 2010;1:391-8.

Akanmu MA, Iwalewa EO, Elujoba AA, Adelusola KA. Toxicity potentials of Cassia fistula fruits as a laxative with reference to Senna. Afr J Biomed Res 2004;7:23-6.

Agnihotri A, Singh V. Effect of Tamarindus indica linn. and Cassia fistula linn. stem bark extracts on oxidative stress and diabetic conditions. Acta Pol Pharm 2013;70:1011-9.

Ilavarasana R, Mallikab M, Venkataraman S. Anti-inflammatory and antioxidant activities of Cassia fistula linn bark extracts. Afr J Tradit Complement Altern Med 2005;2:70-85.

Abid R, Mahmood R. Acute and sub-acute oral toxicity of ethanol extract of Cassia fistula fruit in male rats. Avicenna J Phytomed 2019;9:117-25.



How to Cite

SANORIA, S., Z. L. QADRIE, S. P. GAUTAM, and A. BARWAL. “CASSIA FISTULA: BOTANY, PHYTOCHEMISTRY AND PHARMACOLOGICAL LEVERAGES-A REVIEW”. International Journal of Pharmacy and Pharmaceutical Sciences, vol. 12, no. 6, June 2020, pp. 1-7, doi:10.22159/ijpps.2020v12i6.37310.



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