A REVIEW ON APTAMERS IN GENE THERAPY AND THEIR APPLICATIONS

  • NIKHIL DIXIT Department of Pharmaceutics, H. K. College of Pharmacy, Oshiwara, Mumbai, India
  • GAURANG SAWANT Department of Pharmaceutics, H. K. College of Pharmacy, Oshiwara, Mumbai, India https://orcid.org/0000-0001-8984-2148
  • HAMID KHAN Department of Pharmaceutics, H. K. College of Pharmacy, Oshiwara, Mumbai, India

Abstract

Gene therapy has been initiated as long back from 1990s but is still in development. Research has been continuously going on in this field in order to cure genetic diseases by various techniques. One of these is aptamers. Aptamers are single stranded DNA or RNA molecules made by SELEX technology and have the ability of attaching to a variety of targets namely proteins, peptides, carbohydrates, toxins etc. They find application in skeletal disorders, biosensors, detection of viruses, delivery of drugs, various drug delivery systems, etc.

Keywords: Gene therapy, Cure, Aptamers, Skeletal, Biosensors, Viruses, Drugs

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DIXIT, N., G. SAWANT, and H. KHAN. “A REVIEW ON APTAMERS IN GENE THERAPY AND THEIR APPLICATIONS”. International Journal of Pharmacy and Pharmaceutical Sciences, Vol. 12, no. 12, Dec. 2020, pp. 16-21, doi:10.22159/ijpps.2020v12i12.39241.
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