PRESCRIBING PATTERN OF ANTIBIOTICS AMONG OUTDOOR PATIENTS IN MEDICINE DEPARTMENT OF TERTIARY CARE HOSPITAL IN NORTHERN INDIA

  • SUMAN LATA Demonstrator Department of Pharmacology, Government Medical College Kathua, (JandK) 184101
  • VIJAY KHAJURIA Department of Pharmacology, Government Medical College Kathua, (JandK) 184101
  • VINEETA SAWHNEY Department of Pharmacology, Government Medical College Kathua, (JandK) 184101
  • SANJAY SHAH Department of Pharmacology, Government Medical College Kathua, (JandK) 184101

Abstract

Objective: The objective of the present study was to examine the prescribing pattern of antibiotics in the outpatient department of medicine in a tertiary care hospital.


Methods: This prospective observational study was conducted in department of pharmacology in collaboration with department of medicine of Govt Medical College Kathua for a period of one month. Prescription of all patients attending medicine OPD who were prescribed antibiotics was analysed.


Results: A total of 450 prescription of OPD patients were analysed. Out of these 200 prescriptions of patients had antibiotics prescribed. 98% of prescriptions had oral antibiotics and other 2% were prescribed injectable antibiotics. 70 % of prescriptions were on the single antibiotic and in 30% of prescriptions, fixed-dose combination were prescribed. Cefpodoxime antibiotic was most commonly prescribed in the cephalosporin group, followed by amoxy-clavulanic acid, azithromycin. Irrational prescribing of antibiotics was 34% and it was quite high in our study.


Conclusions: Cefpodoxime was most commonly prescribed in cephalosporin group among all antibiotics. Irrational prescribing was quite high in present study. Our result calls for the urgency of refresher courses like stewardship programmes regarding antibiotic use to avoid irrational usage.

Keywords: Antibiotics, Rational, Prescriptions

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References

1. Bhavnani D, Phatinawin L, Chantra S, Olsen SJ, Simmerman JM. The influence of rapid influenza diagnostic testing on antibiotic prescribing patterns in rural Thailand. Int J Infect Dis 2007;11:355-9.
2. Suttajit S, Wagner Ak, Tantipidoke R, Ross Degnan D, Sitthi Amorn C, Patterns. Appropriateness and predictors of antimicrobial prescribing for adults with upper respiratory infections in urban slum communities of bangkok. Southeast Asian J Trop Med Public Health 2005;36:489-97.
3. Udomthavornsak B, Tatsanavivat P, Patjanasoontorn B, Khomthing R, Bhuripanyo K, Saengnipanthkul S. Intervention of inappropiate antibiotic use at a university teaching hospital. J Med Assoc Thai 1991;74:729-36.
4. Vanitha M, Vineela M. Prescribing pattern of antibiotics in patients attending ENT OPD in a tertiary care hospital. ISOR-JDMS 2017;16:30-3.
5. University of Washington, school of public health and communitymedicine. Antibiotic resistance; 2000.
6. Goossens H. Antibiotic consumption and link to resistance. Clin Microbial Infect 2009;15:12-5.
7. Apisarnthanarak A, Mundy LM. Correlation of antibiotic use and antimicrobial resistance in pratumthani, Thailand, 2000 to 2006. Am J Infect Control 2008;36:681-.2.
8. World Health Oganisation. Promoting rational use of medicine core components. WHO Policy Perspect Med 2002;5:1-6.
9. LE Ramsay. Bridging the gap between clinical pharmacology and rational drug prescibing. Br J Clin Pharmacol 1993;35:575-6.
10. Ronald P Rubin. A brief history of great discoveries in pharmacology: in celebration of the centennial anniversary of the founding of the American society of pharmacology and experimental therauptics. Pharmacol Rev 2007;59:289-359.
11. Tripathi KD. Antimicrobials drugs. General considerations. Essential Med Pharmacol 2019;688:739.
12. Sawhney N, Sawhney V, Khajuria V. Prescribing pattern of antibiotics among postoperative patients admitted in gynaecology and obstetrics department of tertiary care hospital in northern India. Int J Basic Clin Pharmacol 2020;9:300-4.
13. Vlahovic Paleevski V, Merovic M, Paleevski G. Antibiotic utilisation at the university hospital after introducing an antibiotic policy. Eur J Clin Pharmacol 2000;56:97-101.
14. Malihaata, Rozina Haque, Rajat Shanker Roybiswas, Faheem Ulhasan, Happy Rani Barua. Antibiotics prescribing pattern at outpatient department of a tertiary medical college hospital. CMOSHMC J 2018;17:36-9.
15. Ahmad A, Megha R, Irfanul H, Pravina A. Study the prescription pattern of antibiotics in the medicine department in a teaching hospital. IJTPR 2014;6:43-6.
16. Venu Gopal D, Rama Krishna T, Siva Kumar A, Venkata Subhaiah Meda, Ravindra Reddy K. Prescribing pattern of antibiotics in general medicine and paediatrics department of tertiary care hospital. Int J Pharm Pharm Sci 2014;6:221-4.
17. Moghadamnia AA, Mirbolooki MR, Aghili MD. General practitioner prescribing patterns in Babol city, Islamic Republic of Iran. East Mediterr Health J 2002;8:550-5.
18. Sharif SI, Al-Shaqra M, Hajjar H, Shamout A, Wess L. Patterns of drug prescribing in a hospital in dubai, United Arab Emirates. Libyan J Med 2008;3:10-2.
19. Muna KA Oqal, Soha A Elmorsy, Amal K Alfhmy, Reham M Alhadhrami, Rawan A Ekram, Ibtihal A Althobaiti. Patterns of antibiotic prescriptions in the outpatient department and emergency room at a tertiary care center in Saudi Arabia. Saudi J Med Med Sci 2015;3:124-9.
20. TM Vijaykumar, D Sathyavati, T Subhashini, G Sonika, MD Dhanaraju. Assessment of prescribing trends and rationality of drug prescribing. Int J Pharmacogn 2011;7:140-3.
21. Ramnath KV, Shafiya SB. Prescribing pattern of antibiotic usage for urinary tract infection treated in a rural tertiary care hospital. Ind J Pharm Prac 2011;4:57-63.
22. Ahmed A, Parimalakrishan S, Guru PM, Patel I, Manna PK. A study on utilisation pattern of higher generation antibiotics among patients visiting community pharmacies in Chidambaram. Int J Pharma 2012;2:466-71.
23. Steven L Barriere. Monotherapy versus combination antimicrobial therapy: A Review. ACCP 1991;11:1875-9114.
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LATA, S., V. KHAJURIA, V. SAWHNEY, and S. SHAH. “PRESCRIBING PATTERN OF ANTIBIOTICS AMONG OUTDOOR PATIENTS IN MEDICINE DEPARTMENT OF TERTIARY CARE HOSPITAL IN NORTHERN INDIA”. International Journal of Pharmacy and Pharmaceutical Sciences, Vol. 12, no. 12, Dec. 2020, pp. 43-46, doi:10.22159/ijpps.2020v12i12.39711.
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