Maryam Se Hussein, Nahlah Elkudssiah Ismail


There are various developed general-as well as disease-or condition-specific health outcome instruments to assess an impact of asthma among asthmatic children but few of these instruments were developed in paired versions of child and caregiver. The objective of this review was to determine currently available unpaired and paired health outcome instruments for asthmatic children and their caregivers. Systemic search from Medline, Scopus and Science Direct was conducted to identify asthmatic children’s and their caregivers’ health outcomes tracking instruments that characterize basic properties of instruments such as instrument’s developer and the published year, instrument’s description, targeted age and time for completion, items and domains, administration way, scoring and scaling of instrument, type of study setting, tested sample size, availability of instrument in different languages, reliability and validity of the instrument. The results showed in total, 21 instruments were identified whereby 16 of them were administered by either asthmatic children or their caregivers, and remaining (n = 5) have paired version that was administered directly to both asthmatic children and their caregivers. Most of these instruments reported good validity and reliability (Cronbach’s alpha between 0.60-0.95). There is a need to develop more paired disease-specific health outcome instruments targeted both asthmatic children and their caregivers to get full data of the impact and burden of asthma and its health intervention on the respective respondents.



Asthmatic children, Caregivers, Health outcome instrument

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Asthmatic children, Caregivers, Health outcome instrument



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International Journal of Pharmacy and Pharmaceutical Sciences
Vol 7, Issue 8, 2015 Page: 2-16

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Authors & Affiliations

Maryam Se Hussein
Clinical Bio Pharmaceutics Research Group (CBRG), Faculty of Pharmacy, Universiti Teknologi MARA, PuncakAlam Campus, 42300 Bandar Puncak Alam, Selangor, Malaysia

Nahlah Elkudssiah Ismail
Clinical Bio Pharmaceutics Research Group (CBRG), Faculty of Pharmacy, Universiti Teknologi MARA, PuncakAlam Campus, 42300 Bandar Puncak Alam, Selangor, Malaysia

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