IN VITRO ANTI-INFLAMMATORY ACTIVITY OF 4-BENZYLPIPERIDINE

  • Jayashree V Vel's University
  • Bagyalakshmi S
  • Manjula Devi K
  • Richard Daniel D

Abstract

ABSTRACT
Objective: To study the in vitro anti-inflammatory activity of 4-benzylpiperidine.
Methods: This study was conducted to evaluate the in vitro anti-inflammatory activity of 4-benzylpiperidine using in vitro models such as inhibition
of albumin denaturation and proteinase inhibitory activity.
Results: This study revealed the dose-dependent inhibition of protein denaturation and proteinase inhibitory activity by 4-benzylpiperidine.
Conclusion: In the present study, results indicate that the 4-benzylpiperidine possess anti-inflammatory properties. The drug inhibited the heat
induced albumin denaturation and proteinase inhibitory activity. It shows dose-dependent significant activity when compared with a standard drug.
Hence, this study gives an idea that the 4-benzylpiperidine can be used as a lead compound for designing a potent anti-inflammatory drug which can
be used to cure inflammation.
Keywords: Anti-inflammatory activity, 4-Benzylpiperidine, Protein denaturation, Proteinase inhibitory activity.

Author Biography

Jayashree V, Vel's University
Department of Pharmacology

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How to Cite
V, J., B. S, M. D. K, and R. Daniel D. “IN VITRO ANTI-INFLAMMATORY ACTIVITY OF 4-BENZYLPIPERIDINE”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 9, no. 8, Oct. 2016, pp. 108-10, doi:10.22159/ajpcr.2016.v9s2.12623.
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