THE ANTHELMINTIC EFFECTS OF ETHANOL EXTRACT OF CURANGA FEL-TERRAE LEAVES ON ASCARIDIA GALLI


Popi Patilaya, Dadang Irfan Husori, Imam Bagus Sumantri

Abstract


ABSTRACT
Objective: This study was to investigate the anthelmintic effects of ethanol extract of Curanga fel-terrae leaves on Ascaridia galli.
Methods: Extract of C. fel-terrae was prepared by percolating the dried powder of the plant leaves. To observe anthelmintic effects, A. galli was
exposed to the plant extract solutions in different concentrations at room temperature for 72 hrs. Sodium chloride 0.9%, sodium carboxymethyl
cellulose 0.5%, and albendazole 0.1% were served as negative control, solvent control, and positive control, respectively. The anthelmintic effects
were determined by observing the time taken for paralysis and the time taken for death of A. galli during experiment.
Results: The results demonstrated that there were no different effects between negative and solvent controls. However, the ethanol extract of
C. fel-terrae leaves exhibited significantly paralysis and death effects toward A. galli. The plant extracts at the concentration of 100 mg/ml showed
similar anthelmintic effects with albendazole 0.1%. This study also indicated that the paralysis and death effects of plant extract were shorter when
the worms exposed with the concentration above of 100 mg/ml.
Conclusion: This study indicated that the ethanol extract of C. fel-terrae leaves has potential anthelmintic effects on A. galli.
Keywords: Curanga fel-terrae, Ascaridia galli, Anthelmintic, Helminthiasis, Ascariasis.

 


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About this article

Title

THE ANTHELMINTIC EFFECTS OF ETHANOL EXTRACT OF CURANGA FEL-TERRAE LEAVES ON ASCARIDIA GALLI

DOI

10.22159/ajpcr.2017.v10i3.15504

Date

01-03-2017

Additional Links

Manuscript Submission

Journal

Asian Journal of Pharmaceutical and Clinical Research
Vol 10 Issue 3 March 2017 Page: 117-119

Print ISSN

0974-2441

Online ISSN

2455-3891

Statistics

179 Views | 252 Downloads

Authors & Affiliations

Popi Patilaya
Universitas Sumatera Utara
Indonesia

Dadang Irfan Husori
Universitas Sumatera Utara
Indonesia

Imam Bagus Sumantri
Universitas Sumatera Utara
Indonesia


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