A REVIEW ON PHYTOSOMES: NOVEL APPROACH FOR HERBAL PHYTOCHEMICALS


Arun Kumar, Bimlesh Kumar, Sachin Kumar Singh, Barinder Kaur, Saurabh Singh

Abstract


 

 The poor oral bioavailability of polyphenolic compound can be enhanced through the incorporation of them into phospholipid based self-assembled delivery system, i.e. popularly known as phytosome. “Phyto” means plants and “some” resembles a covering around/or a structure. Phytosome is generally prepared by reacting one or two moles of polyphenolic phytoconstituents and phospholipid. It may be either in the ratio of 1:1 and 1:2. By using phytosomes, one can also achieve enhanced rate and extent of the passage of lipophilic herbal constituents across lipid membrane that explains its character as a carrier as well as acid labile herbal drugs could also be protected in gastrointestinal tract. There are number of products available in the market that contains phytosomal drug delivery system such as Ginkgo biloba, Silybum marianum, and Camellia sinensis. The present review describes an updated overview of preparation of phytosomes, advancement in phytosomes technology, various herbal drugs for which phytosomes have been used as a carrier, its commercial availability and applications.


Keywords


Phytosomes, Novel drug delivery system, Phospholipid.

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About this article

Title

A REVIEW ON PHYTOSOMES: NOVEL APPROACH FOR HERBAL PHYTOCHEMICALS

Keywords

Phytosomes, Novel drug delivery system, Phospholipid.

DOI

10.22159/ajpcr.2017.v10i10.20424

Date

01-09-2017

Additional Links

Manuscript Submission

Journal

Asian Journal of Pharmaceutical and Clinical Research
Vol 10 Issue 10 October 2017 Page: 41-47

Print ISSN

0974-2441

Online ISSN

2455-3891

Statistics

118 Views | 134 Downloads

Authors & Affiliations

Arun Kumar
Department of Ayurvedic Pharmacy, Ayurvedic Pharmacy, School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab - 14441, India
India

Bimlesh Kumar
Department of Pharmacy, School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab - 14441, India.
India

Sachin Kumar Singh
Department of Pharmacy, School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab - 14441, India.
India

Barinder Kaur
Department of Ayurvedic Pharmacy, Ayurvedic Pharmacy, School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab - 14441, India
India

Saurabh Singh
Department of Ayurvedic Pharmacy, Ayurvedic Pharmacy, School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab - 14441, India
India


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