STUDY ON APHRODISIAC ACTIVITY OF OLEA DIOICA ROXB. BARK, LEAF EXTRACTS, AND ITS PURE COMPOUND USING WISTAR ALBINO RATS


Ashwathanarayana R, Raja Naika

Abstract


Objectives: We aimed to assess the effects of O. dioica Roxb. leaf and bark extract and its isolated constituent benzeneethanol, 4-hydroxy- on aphrodisiac activity in rats using different standard aphrodisiac parameters.

Methods: To determine the aphrodisiac activity several parameters were observed. These include measuring and observing the mount frequency (MF), mount latency (ML), intromission frequency (IF), intromission latency (IL), anogenital sniffing (AS), and genital grooming (GG).

Results: The aphrodisiac activity of O. dioica Roxb. leaf and bark extracts and its pure compound were studied on Wistar albino rats at different dosages. The parameters observed during the study were MF, ML, IF, IL, AS, and GG. The results revealed that the crude extracts showed dose-dependent activity in all the concentration, in that, ethanolic leaf extract showed excellent activity compared to ethanolic bark extract and pure compound benzene ethanol 4-hydroxy.

Conclusion: Results showed the excellent aphrodisiac activity of O. dioica Roxb. leaf and bark ethanolic extracts. However, the major compound benzeneethanol, 4-hydroxy- was not responsible for the aphrodisiac activity, may be the minor compounds even though in minor concentration in the extract influence the sexual activity in tested animals.


Keywords


Olea dioica Roxb, Benzeneethanol, 4-hydroxy-, Aphrodisiac activity.

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About this article

Title

STUDY ON APHRODISIAC ACTIVITY OF OLEA DIOICA ROXB. BARK, LEAF EXTRACTS, AND ITS PURE COMPOUND USING WISTAR ALBINO RATS

Topics

Botany

Keywords

Olea dioica Roxb, Benzeneethanol, 4-hydroxy-, Aphrodisiac activity.

DOI

10.22159/ajpcr.2017.v10i12.21197

Date

01-12-2017

Additional Links

Manuscript Submission

Journal

Asian Journal of Pharmaceutical and Clinical Research
Vol 10 Issue 12 December 2017 Page: 85-98

Print ISSN

0974-2441

Online ISSN

2455-3891

Statistics

10 Views | 33 Downloads

Authors & Affiliations

Ashwathanarayana R
Department of PG Studies and Research in Applied Botany, Kuvempu University, Jnanasahyadri, Shankaraghatta, Shimoga - 577 451, Karnataka, India.
India

Raja Naika
Department of PG Studies and Research in Applied Botany, Kuvempu University, Jnanasahyadri, Shankaraghatta, Shimoga - 577 451, Karnataka, India.
India


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